Why Should You Not Smoke

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Information about Why Should You Not Smoke

Published on December 16, 2016

Author: DrShadSalimAkhterAkh

Source: slideshare.net

1. Tobacco- Why It Should Not Be Used Prof. Shad Salim Akhtar MBBS, MD, MRCP(UK), FRCP(Edin), FACP(USA), FICA (USA) Fellow Association of Members UICC Member Global Cancer Control Committee UICC Overseas Advisor Royal College of Physicians of UK Consultant Medical Oncologist & Director Hakim Sanaullah Specialist Hospital & Cancer Center, Sopore, Kashmir, J &K

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3. 3 Nicotiana tabacum

4. When Was Tobacco Cultivated?When Was Tobacco Cultivated? 14921492 6000 BC6000 BC 1 BC1 BC 15311531

5. 1492-10-12: On this bright morning Columbus and his men set foot on the New World for the first time, landing on the beach of San Salvador Island or Samana Cay in the Bahamas, or Gran Turk Island. The indigenous Arawaks, possibly thinking the strange visitors divine, offer gifts. Columbus wrote in his journal, “the natives brought fruit, wooden spears, and certain dried leaves which gave off a distinct fragrance.” As each item seemed much-prized by the natives; Columbus accepted the gifts and ordered them brought back to the ship. The fruit was eaten; the pungent "dried leaves" were thrown away.”

6. 8 1492-11: Rodrigo de Jerez and Luis de Torres, in Cuba searching for the Khan of Cathay (China), are credited with first observing smoking. They reported that the natives wrapped dried tobacco leaves in palm or maize "in the manner of a musket formed of paper." After lighting one end, they commenced "drinking" the smoke through the other.

7. 9 Jerez Becomes First European Smoker Jerez became a confirmed smoker, and is thought to be the first outside of the Americas. He brought the habit back to his hometown, but the smoke billowing from his mouth and nose so frightened his neighbors he was imprisoned by the holy inquisitors for 7 years. By the time he was released, smoking was a Spanish craze.

8. Types of TobaccoTypes of Tobacco Manufactured CigarettesManufactured Cigarettes BidisBidis CigarsCigars KreteksKreteks PipesPipes ClayClay WaterWater SticksSticks Chewing TobaccoChewing Tobacco SnuffSnuff

9. Betel leaves Betel nut Lime

10. is still a cigarette, and still as dangerous! 3 times CO and 5 times Tar compared to a cigarette a cigarette by any other name …

11. “Short, snappy, easily attempted, easily completed or just as easily discarded before completion – the cigarette is the symbol of the machine age." New York Times, 1925

12. Quantum of the ProblemQuantum of the Problem Number of regular smokersNumber of regular smokers 1.3 billion1.3 billion  Third of the word population aged >=15yrsThird of the word population aged >=15yrs 47.5% men and 10.3% women smoke47.5% men and 10.3% women smoke 82-90,000 young people start82-90,000 young people start smoking dailysmoking daily 15 billion cigarettes are smoked daily15 billion cigarettes are smoked daily 5.5 trillion consumed in 20005.5 trillion consumed in 2000 Other tobacco (smokeless tobacco) useOther tobacco (smokeless tobacco) use data???data???

13. Ill EffectsIll Effects HealthHealth EconomicEconomic SocialSocial25

14. Tobacco CarcinogenesisTobacco Carcinogenesis >4000 chemicals>4000 chemicals >60 carcinogenic>60 carcinogenic Hecht SS: Nat Rev Cancer 2003;3:733

15. Tobacco CarcinogensTobacco Carcinogens Polycyclic aromatic hydrocarbons (PAH)Polycyclic aromatic hydrocarbons (PAH)  Benzo[a]pyrene first to be recognizedBenzo[a]pyrene first to be recognized Causes mutaion in TP53 tumor suppressor geneCauses mutaion in TP53 tumor suppressor gene Nitrosamines (TSNA)Nitrosamines (TSNA)  Most prevalent strong carcinogens inMost prevalent strong carcinogens in unburned and smokeless tobaccounburned and smokeless tobacco Aromatic aminesAromatic amines Weaker carcinogens like acetaldehydeWeaker carcinogens like acetaldehyde JS Levitz et al: Med Clin N Am 2004; 88:1655

16. Tobacco SmokeTobacco Smoke Also found inAlso found in AcetoneAcetone Paint StripperPaint Stripper AmmoniaAmmonia Floor CleanerFloor Cleaner ArsenicArsenic Ant poisonAnt poison ButaneButane Lighter fuelLighter fuel CadmiumCadmium Car BatteriesCar Batteries Carbon MonoxideCarbon Monoxide Car exhaust fumesCar exhaust fumes DDTDDT InsecticideInsecticide Hydrogen CyanideHydrogen Cyanide Gas ChambersGas Chambers MethanolMethanol Rocket FuelRocket Fuel NaphtaleneNaphtalene Moth BallsMoth Balls TouleneToulene Industrial SolventIndustrial Solvent Vinyl ChlorideVinyl Chloride PlasticsPlastics LeadLead Lead based paintsLead based paints AcrolienAcrolien A chemical weaponA chemical weapon FormaldehydeFormaldehyde Embalming fluidEmbalming fluid

17. Tobacco CarcinogenesisTobacco Carcinogenesis >4000 chemicals>4000 chemicals >60 carcinogenic>60 carcinogenic Nicotine content important to causeNicotine content important to cause addictionaddiction  Not carcinogenicNot carcinogenic  ToxicToxic Hecht SS: Nat Rev Cancer 2003;3:733 Combination needed

18. Nicotine Delivery Device Addicting Nicotine 4000 Chemicals 60 Carcinogens Perfect Killing Machine Hecht SS: Nat Rev Cancer 2003;3:733

19. Aortic aneurysm Stroke Sudden cardiac death

20. Preterm delivery Reduced fertility Reduced oxygen to placenta Sudden infant death syndrome Early menopause Irregular menstrual bleeding Premature wrinkling and aging

21. Smoking-Related Health Risks-Cancers Cancer Bladder Cervical Kidney Larynx Lung Mouth Pancreatic Throat

22. 90% of new smokers begin as teenagers; more than 5 million of whom will eventually die as a result Source: CDC Office of Smoking and Health; National Center for Tobacco-Free Kids

23. Of young adults who started smoking in their teens and continue to smoke cigarettes regularly: • about 25% will die prematurely in middle age • about 25% will die prematurely in old age Smoking and the Risk of Premature Death

24. Tobacco Related DeathTobacco Related Death 8.8% deaths globally8.8% deaths globally 5 million per year5 million per year 13,500 per day13,500 per day Every 6.5 seconds someoneEvery 6.5 seconds someone dies from tobacco usedies from tobacco use Death toll to rise to 10 million per yearDeath toll to rise to 10 million per year  7 million in non industrialized countries7 million in non industrialized countries Half the people smoking today will beHalf the people smoking today will be eventually killed by tobaccoeventually killed by tobacco

25. Every 6.5 secondsEvery 6.5 seconds someone diessomeone dies from tobacco usefrom tobacco use

26. The World Health OrganisationThe World Health Organisation describes smoking as an:describes smoking as an: epidemicepidemic that will causethat will cause 1/3 of all adult deaths1/3 of all adult deaths world-wide by 2020world-wide by 2020

27. Bryan Curtis started smoking at 13, never thinking that 20 years later it would kill him and leave a wife and children alone. In his last weeks, he set out with a message for young people.32 yrs 33 yrs

28. Ill EffectsIll Effects HealthHealth EconomicEconomic SocialSocial54

29. What is the economic impact ofWhat is the economic impact of smoking?smoking? Cost of smoking--- directCost of smoking--- direct Loss of income due to prematureLoss of income due to premature deathdeath Cost of medical careCost of medical care Loss of propertyLoss of property Loss of time of family for care takingLoss of time of family for care taking

30. Direct Medical Costs:Direct Medical Costs: Consequences of SmokingConsequences of Smoking Physicians $20.2 Billion Hospitals $39.9 Billion Nursing Homes $9.8 Billion Home Health Care $1.9 Billion Prescription Drugs $8 Billion Estimated $80+ Billion Total Direct Medical Care Costs in 1993

31. Economic Impact of SmokingEconomic Impact of Smoking

32. Every year 1,000,000 fires started by children using cigarette lighters

33. Ill EffectsIll Effects 62 HealthHealth EconomicEconomic SocialSocial

34. Teens who smoke are — • 3 times more likely to use alcohol • 8 times more likely to use marijuana • 22 times more likely to use cocaine — than teens who don’t

35. More than 3,000 kids under 18 try smoking every day; that’s more than 1,000,000 every year. CDC, 1997

36. We react to one but to the other!!!!!

37. Tobacco CarcinogenesisTobacco Carcinogenesis Mainstream smokeMainstream smoke  Inhaled through the column ofInhaled through the column of cigarettecigarette Sidestream (passive, secondSidestream (passive, second hand smoke)hand smoke)  Emitted from the burning coneEmitted from the burning cone of the cigaretteof the cigarette  Has similar chemicals butHas similar chemicals but higher level of carcinogenshigher level of carcinogens “Particulate phase” only 5% of all output is visible

38. Passive or second handPassive or second hand smokesmoke  One of the most dangerousOne of the most dangerous cancer-causing agents incancer-causing agents in humanshumans  Group A carcinogenGroup A carcinogen

39. 74 Parents warned about new 'tobacco sticks' A new tobacco product being sold in Kansas has prompted warnings from state health officials, who say the tiny "smokeless tobacco sticks" could pose a danger to children. Altria Group Inc., the parent company of Philip Morris USA and U.S. Smokeless Tobacco Co., recently began test- marketing the tobacco-coated sticks at select retailers in Kansas, including Wichita, said company spokesman Ken Garcia. The sticks, sold in matchbook-like packs under the brand names Marlboro and Skoal, are aimed at adult smokers and snuff users who want a smokeless, spit-free alternative, ….. BY SUZANNE PEREZ TOBIAS Thu, Jun. 02, 2011

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41. Murder!Murder!

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