Takotsubo cardiomyopathy or so-called heart break syndrome

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Information about Takotsubo cardiomyopathy or so-called heart break syndrome
Education

Published on March 2, 2014

Author: Giiang

Source: slideshare.net

Description

A presentation about heart break syndrome

Takotsubo cardiomyopathy or heartbreak syndrome

Takotsubo • “Takotsubo” is from the Japanese name for an octopus trap, which has a shape that is similar to the apical ballooning configuration of the left ventricle (LV) in systole in the typical form of this disorder.

Cardiomyopathy

Takotsubo Cardiomyopathy • Takotsubo cardiomyopathy is a weakening of the left ventricle, the heart's main pumping chamber. • Usually it’s the result of severe emotional or physical stress. – E.g. a sudden illness, the loss of a loved one, a serious accident, or a natural disaster such as an earthquake.

Historical Background

Symptoms • Chest pain and shortness of breath after severe stress (emotional or physical) • Electrocardiogram abnormalities that mimic those of a heart attack • No evidence of coronary artery obstruction

Symptoms • Movement abnormalities in the left ventricle • Ballooning of the left ventricle

Etipology • The causes are not fully understood yet. However, there are several mechanisms were proposed. • Multivessel coronary artery spasm, impaired cardiac microvascular function, impaired myocardial fatty acid metabolism, acute coronary syndrome with reperfusion injury, etc.

Epidemiology • 1.7-2.2% of patients who had suspected acute coronary syndrome were subsequently diagnosed with takotsubo cardiomyopathy • Races: 57.2% were Asian, 40% were Caucasian, and 2.8% were other races. • A mean patient age of 67 years • Nearly 90% of reported cases involve postmenopausal women.

Prognosis • Nearly 95% of patients experiencing complete recovery within 4-8 weeks. • The recurrence rate varies but is estimated at 6%. Estimates of mortality rates have ranged from 1-3.2%. • Fatal complications such as left ventricular free wall rupture.

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