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Session 16D - Frontal Lobes IV and exam review

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Information about Session 16D - Frontal Lobes IV and exam review
Education

Published on March 13, 2014

Author: FraserNelson

Source: slideshare.net

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PSYC 3390 NEUROPSYCHOLOGY UNIT 16D - THE FRONTAL LOBES INSTRUCTOR: FRASER NELSON

IMPAIRED SOCIAL AND SEXUAL BEHAVIOUR • CHANGES IN PERSONALITY – PSEUDODEPRESSION • APPEARS AFTER LESIONS OF THE LEFT FRONTAL LOBE • OUTWARD APATHY, INDIFFERENCE, LOSS OF INITIATIVE • REDUCED SEXUAL INTEREST, LITTLE OR NO VERBAL OUTPUT

IMPAIRED SOCIAL AND SEXUAL BEHAVIOUR • CHANGES IN PERSONALITY (CONTINUED) – PSEUDOPSYCHOPATHY • APPEARS AFTER LESIONS OF THE RIGHT FRONTAL LOBE • IMMATURE BEHAVIOR, LACK OF TACT AND RESTRAINT • PROMISCUOUS SEXUAL BEHAVIOR • COARSE LANGUAGE, LACK OF SOCIAL GRACES, INCREASED MOTOR ACTIVITY

SYMPTOMS OF FRONTAL LOBE LESIONS • IMPAIRED SOCIAL AND SEXUAL BEHAVIOR – DEFICITS IN SOCIAL AND SEXUAL BEHAVIOR • ORBITOFRONTAL LESIONS – REDUCE INHIBITIONS AND MAY INTRODUCE ABNORMAL SEXUAL BEHAVIOR – LEADS TO DEFICITS IN IDENTIFYING FACIAL EXPRESSIONS • DORSOLATERAL LESIONS – REDUCE INTEREST IN SEXUAL BEHAVIOR

SYMPTOMS OF FRONTAL LOBE LESIONS • BUTTER & SNYDER (1972) – REMOVED THE ORBITOFRONTAL CORTEX OF A GROUP OF MALE RHESUS MONKEYS AND OBSERVED THE CHANGES IN SPECIES-SPECIFIC AGGRESSIVE AND AVERSIVE BEHAVIOURS – LESIONED MONKEYS DISPLAYED ATTENUATED AGGRESSIVE REACTIONS AND ENHANCED AVERSIVE REACTIONS IN A NUMBER OF SETTINGS, INCLUDING BEING REINTRODUCED BACK INTO THEIR COLONIES – THEY DID NOT LOSE THE CAPACITY TO EXECUTE AGGRESSIVE BEHAVIOUR BUT RATHER THEIR ABILITY TO INTERPRET WHEN IT IS APPROPRIATE TO RESPOND WITH AGGRESSION • STUDIES OF LESIONED MONKEYS IN NATURALIZED ENVIRONMENTS – FOLLOWING FRONTAL-LESIONS, MONKEYS REINTRODUCED INTO THEIR COLONIES QUICKLY FELL TO THE BOTTOM RANKS OF THE SOCIAL HIERARCHY – LESION LED TO AN IMPAIRMENT IN APPROPRIATE RESPONSE-SELECTION WITHIN COMPLEX SOCIAL INTERACTIONS

SYMPTOMS OF FRONTAL LOBE LESIONS • SPATIAL DEFICITS? – MAY BE A ROLE FOR THE FRONTAL LOBE IN SELECTING VISUAL LOCATIONS • SYMPTOMS ASSOCIATED WITH DAMAGE TO THE FRONTAL FACIAL AREA – SENSORY AND MOTOR FUNCTIONS OF THE FACE ARE PRESERVED AFTER DAMAGE – LEFT: LOSS OF VERBAL FLUENCY – RIGHT: LOSS OF DESIGN FLUENCY

DISEASES AFFECTING THE FRONTAL LOBE • SCHIZOPHRENIA – ABNORMALITY IN THE MESOCORTICAL DOPAMINERGIC PROJECTION – DECREASE IN BLOOD FLOW TO THE FRONTAL LOBES, AND FRONTAL LOBE ATROPHY – PARTICULAR LOSS OF GRAY MATTER IN THE FRONTAL LOBES, STG, AMYGDALA, AND THE HIPPOCAMPUS + ENLARGEMENT OF THE VENTRICLES – IMPAIRED TEMPORAL MEMORY DUE TO DAMAGE TO THE DL-PFC (BARCH ET AL., 2001)

DISEASES AFFECTING THE FRONTAL LOBE • PARKINSON’S DISEASE – LOSS OF DOPAMINE CELLS IN THE SUBSTANTIA NIGRA THAT PROJECT TO THE PREFRONTAL CORTEX Image credit: http://www.parkinsondisease.in/

DISEASES AFFECTING THE FRONTAL LOBE • KORSAKOFF’S – ALCOHOL-INDUCED DAMAGE TO THE DORSOMEDIAL THALAMUS AND A DEFICIENCY IN FRONTAL LOBE CATECHOLAMINES

CLINICAL NEUROPSYCHOLOGICAL ASSESSMENT OF FRONTAL LOBE DAMAGE

ASYMMETRY OF THE FRONTAL LOBES • LEFT FRONTAL LOBE – GREATER INVOLVEMENT IN PROCESSING LANGUAGE – ENCODING MEMORIES • RIGHT FRONTAL LOBE – GREATER INVOLVEMENT IN PROCESSING NON-VERBAL MOVEMENTS, FACIAL EXPRESSION – RETRIEVING MEMORIES • BILATERAL REGIONS OF THE FRONTAL LOBE WORK IN A NETWORK-MODEL FOR ACHIEVING ASPECTS OF PERCEPTION, RESPONSE SELECTION, EXECUTIVE FUNCTIONS, MEMORY, AND PROBLEM SOLVING

EXAM POSTPONED TO MONDAY, MARCH 17, 2014

END OF LECTURE

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