SaaS - science as a service

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Information about SaaS - science as a service
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Published on May 10, 2014

Author: cytang

Source: slideshare.net

Description

IT infrastructure of HealthCare and Bio-Tech

11 SaaS Science as a Service Abner Huang <abnercyh@cs.nthu.edu.tw> CSBB Lab., NTHU Dec. 14, 2011 Figure from GEN News Highlights: Jul 2, 2010

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Science is different 3

Science as a service 4

6 Evolution of Biomedical researchers

7 Nature: Milestones in DNA 1977 DNA sequencing 1990 BLAST 2002 UCSC Genome browser 2004 Ensembl Figure from http://www.nature.com/milestones/miledna/timeline.html

8 The Trend of NGS BRIEFINGS IN BIOINFORMATICS. VOL 11. NO 5. 484 ^ 498

9 Illumina's Certified Service Providers www.illumina.com/services/cspro.ilmn

10 Personal Genome and Clinical Business

11 http://news.sciencemag.org/scienceinsider/2010/06/uk-to-sequence-10000-genomes.html

12 NHGRI’s New Sequencing Projects • Genome Sequencing – Near $85 million in the first year • Mendelian Disorders – $12 million per year • Clinical Exploration – $10.3 million per year • Informatics Tools – $20 million for four years 12 http://www.genome.gov/27546261

13 The Trend of NGS ivory.idyll.org/permanent/lstein-ngs-capacity.png

1414 Challenges for Biomedical researchers

15 Solve It Using Cloud Computing http://genomebiology.com/2010/11/5/207

16 ``Cloud Computing’’ in PubMed

17 Biomedical Institutes hug cloud computing • J. Craig Venter Institute released JCVI CLOUD BIO-LINUX • IBM eX5 Improves Next Generation Sequencing for Sanger Institute • ISB made Trans-Proteomic Pipeline (TPP) on clouds.

18 Startup Companies

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Galaxy Cloud 21 http://www.biomedcentral.com/1471-2105/11/S12/S4

Galaxy Cloud 22

Parallel Algorithms Spectrum 23

CloudBurst 24

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RNAseq Unified Mapper (RUM) 26

Myrna 27

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Contrail 29

What’s Next? • Alternative expression • Allelic expression • Structural variation • Epigenomics • Metagenomics • Biological data/text mining • Hapotype/Hapomap • K thousand genomes 30

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NGS economics Biomedical Researcher Instrument vendors Sequencing outsourcing Analysis outsourcing Consultants 33

NGS economics Biomedical Researcher Instrument vendors Sequencing outsourcing Analysis outsourcing ODM Consultants 34

NGS economics on clouds Biomedical Researcher Instrument vendors Sequencing outsourcing Analysis outsourcing Fabless ODM Consultants 35 2 1 3 4

Voila! RNA-Seq Data Analysis 36

38 IaaS Infrastructure as a Service PaaS Platform as a Service SaaS Software as a Service Cloud Service Models for Scientists www.spoutingshite.com/wp-content/uploads/2008/12/saas_and_cloud_computing.ppt

39 Eating your own dog food

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Science as a service Service as a science 42

Loose coupled interdisciplinary 43

Service science and cloud computing • HPC on cloud computing of NGS • Data Transfer Bottlenecks • Streaming Computing • Cost of Cloud Storage • Community Cloud Developing • App. Exchange of bioinformatics 44

THANK YOU 45

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