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Information about Rct

Published on March 13, 2014

Author: abdulwasay789

Source: slideshare.net

By Dr Aijaz Ahmed Sohag HOD Com Medicine Dept Edit by: Abdulwasay Baloch Amna Inayat Medical College Randomized Control Trial (RCT)

Randomized Control Trial- RCT  Experiment methods where individuals are randomly allocated to an experimental or a control group  The effect or intervention is compare between the two groups  Two Key Features are: 1. Randomization 2. Controlled  These trials are BLINDED  Single blind means the patients do not know what the intervention is  Double blind means that netither the patient nor the researcher knows what the intervention or drug is  Triple blind means Analysis team also does not know which is experimental and which is control group

Plus Point of the Study  A unique strength of this study is that it eliminated both confounding bias both known and unknown

Drawbacks of RCT  External validity refers to extent to which the results can be generalized to a boarder community  For RCT , including person is first screened, then only they are included in trial – this may lead to that volunteers selected different from those who do not  RCT cannot be used in instances such as exposure to harm to harmful materials such as , Toxins, Bacteria

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