PPT_Manjinder

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Information about PPT_Manjinder
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Published on January 29, 2016

Author: manjinder327387

Source: authorstream.com

Plasma and Plasma proteins: Dr. Manjinder Kaur Plasma and Plasma proteins Plasma: Plasma Clear, straw coloured fluid Constitutes 55% of blood volume Consists of water 91% solids 9% Plasma proteins: Plasma proteins 7% of plasma Concentration -7.4gm% (6.4 to 8.3%) Plasma Proteins: Albumin : 60% : helps maintain blood osmotic pressure, transport lipid, hormones, other solutes and maintains pH Globulin : 36%: transport fat soluble vitamins, blood clotting, formation of antibodies Fibrinogen : 4%: blood coagulation Plasma Proteins Synthesis of plasma proteins: Synthesis of plasma proteins Embryo - mesenchymal cells Adults – liver Albumin & Fibrinogen – RE cells of liver  and  globulin – liver, spleen & bone marrow  globulin – B- lymphocytes, plasma cells Plasma protein deficiency: Plasma protein deficiency CAUSES Hepatic failure  decreased or no synthesis Nephrotic syndrome  heavy loss Prolonged protein malnutrition  decreased availability Mal absorption syndrome  less or no absorption CONSEQUENSES Edema due to decreased plasma oncotic pressure Functions of plasma proteins: Functions of plasma proteins Reserve proteins  during prolonged starvation it provides protein through amino acid pool Blood clotting Fibrinogen---fibrin (blood clot) Exert Colloid osmotic pressure 25 to 30 mm Hg, Albumin Functions of plasma proteins: Functions of plasma proteins Viscosity Contributed max. by Fibrinogen Because of asymmetrical shape Immunity Gamma globulin Rouleaux formation Fibrinogen and globulin Functions of plasma proteins: Functions of plasma proteins Transport function Carbon dioxide , Hormones, Drugs, Calcium, Copper ( ceruloplasmin ), Free hemoglobin ( hepatoglobin ), bilirubin Buffer

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