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Published on May 2, 2008

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European Information Society Technologies:  European Information Society Technologies Framework 7 eHealth Opportunities FP7: ICT Challenge 5 - Towards sustainable and personalised healthcare:  FP7: ICT Challenge 5 - Towards sustainable and personalised healthcare Diane Whitehouse diane.whitehouse@ec.europa.eu ICT for Health DG Information Society & Media European Commission Challenges for European Health Systems:  Challenges for European Health Systems Pressure on healthcare systems Demographic changes more people will require prolonged care Increased prevalence of chronic diseases substantial part of the overall healthcare costs Citizens’ expectations for high-quality care Rising healthcare costs faster than the economic growth itself Require changes in the way: healthcare is delivered medical knowledge is managed & transferred in clinical practice Aims:  Aims Multidisciplinary research to support: Improved productivity of healthcare systems patient care at the point of need health information processing Continuous and more personalised care solutions informed & responsible participation of patients and informal carers respond to the needs of elderly people Prevention and prediction of diseases save lives and avoid costly treatments Higher patient safety optimise medical interventions and prevent errors Industrial leadership European eHealth and medical imaging/devices industry attract pharmaceutical research back in Europe Aims:  Aims Integrated, holistic approach addressing: User needs Technological development Personal data security, confidentiality, privacy Reimbursement Legal framework Validation quantitative indicators of their added value and potential impact Integration in healthcare processes interoperability with eHealth systems encourage changes towards new delivery models Strategic Research Targets:  Strategic Research Targets Three main elements: Personal Health Systems Patient Safety Virtual Physiological Human Personal Health Systems:  Personal Health Systems Key facilitators for: Continuity of care Preventive & personalised care Citizen-centred care citizen empowerment preventive lifestyle & early diagnosis disease management independent living for ageing society Personal Health Systems:  Personal Health Systems Benefits for all: health conscious who wish to stay fit healthy individuals at risk who wish to maintain normal health status chronically ill patients elderly persons or people in need, who want to live independently outside care institutions In the form of: wearable implantable portable systems point-of-care systems Personal Health Systems:  Personal Health Systems Examples of FP6 projects MYHEART (http://www.hitechprojects.com/euprojects/myheart/) Wearable systems (intelligent textiles) for prevention, early diagnosis and management of cardiovascular diseases OFSETH (www.ofseth.org) Textiles with optical sensors for physiological monitoring HEARTFAID (www.heartfaid.org) Knowledge-based platform for heart failure management SMARTHEALTH (www.smarthealthip.com) and MICROACTIVE (www.sintef.no/microactive) Point of care devices for cancer screening (breast, cervical and colorectal cancer) FP7 Objective ICT 2007.5.1 – Personal Health Systems for Monitoring and Point of Care diagnostics:  FP7 Objective ICT 2007.5.1 – Personal Health Systems for Monitoring and Point of Care diagnostics Focus on: (a) Personalised (health status) monitoring For people at risk or chronically ill Wearable or portable/mobile ICT systems Enable remote monitoring & care Multi-parametric information (physiological; biochemical; activity, location, social and environmental context) Intelligent systems to correlate multi-parametric data with expert biomedical knowledge aid diagnosis user support Interoperable with electronic medical records FP7 Objective ICT 2007.5.1 – Personal Health Systems for Monitoring and Point of Care diagnostics:  FP7 Objective ICT 2007.5.1 – Personal Health Systems for Monitoring and Point of Care diagnostics Focus on: a1) Chronic disease management intelligent closed-loop approaches detect and assess trends and episodes facilitate adaptive care remote management, avoiding hospitalisation promote doctor-patient interaction potential for integration in the healthcare process a2) Preventive monitoring for people at risk identify evolving patterns/trends in health & lifestyle parameters indicate elevated risks of disease development reveal episodes at early stages facilitate personalised guidance encourage citizen compliance prompt for early medical intervention FP7 Objective ICT 2007.5.1 – Personal Health Systems for Monitoring and Point of Care diagnostics:  FP7 Objective ICT 2007.5.1 – Personal Health Systems for Monitoring and Point of Care diagnostics Focus on: (b) Point-of-Care diagnostics Multi-analyte screening at primary care (GP offices) Portable or handheld devices (based on LoC, microarrays, etc.) Multiple tests (e.g. genome, proteome, metabolome levels) Identify disease predisposition Early diagnosis of diseases & their recurrence Assistance to treatment dosage advice suitability of drug use Significant advances in: sensitivity and specificity, data processing, analysis and quality control Interface with hospital and laboratory information systems & electronic medical records FP7 Objective ICT 2007.5.1 – Personal Health Systems for Monitoring and Point of Care diagnostics:  FP7 Objective ICT 2007.5.1 – Personal Health Systems for Monitoring and Point of Care diagnostics (c) Additional Support Actions on: R&D roadmap on Personal Health Systems emerging technologies and potential applications user demand and business aspects ethical and legal considerations Wireless transmission of health-related information reliability aspects need for exclusive radio frequency bands? Interoperability of Personal Health Systems with other eHealth systems promotion and recommendations for continuous care FP7 Objective ICT 2007.5.1 – Personal Health Systems for Monitoring and Point of Care diagnostics:  FP7 Objective ICT 2007.5.1 – Personal Health Systems for Monitoring and Point of Care diagnostics When : Call 1 Instruments: (a) Personalised Monitoring : IPs (b) Point of Care diagnostics : IPs (c) Coordination and Support Actions: CSAs Patient safety – Dimension of the problem:  Patient safety – Dimension of the problem > 1 M. patients in US suffer injuries each year as a result of broken health care processes and system failures. > 1/2 of U.S. patients receive known “best practice” treatments for their illnesses and < 1/2 physician practices use recommended processes for care. 30 -40% of every dollar spent on health care in US, is spent on costs associated with “overuse, underuse, misuse, duplication, system failures, unnecessary repetition, poor communication, and inefficiency” In Europe:  In Europe Department of Health in UK estimates that 1/10 patients admitted to NHS hospitals will be unintentionally harmed Patient safety incidents cost the NHS in UK an estimated £2 billion a year in extra bed days, in addition hospital acquired infections add a further £1 billion to these costs. In the Netherlands, approx. 800,000 Dutch people over the age of 18 have been the victim of errors due to the inadequate transfer of medical information. Advanced Risk assessment and Patient safety:  Advanced Risk assessment and Patient safety FP6 - Projects related to Patient safety : Reserch projects PIPS (Personalised Information Platform for life and health Services) http://www.pips.eu.org COCOON (Integrated Project aimed at supporting health care professional in reducing risk management in their daily practices ) http://www.cocoon-health.com/ Study Impact of ICT on Patient Safety and Risk Management in Healthcare (12 month, started January 2006) see http://www.ehealth-for-safety.org/ FP7 Objective ICT 2007.5.2 – Advanced ICT for Risk assessment and Patient Safety:  FP7 Objective ICT 2007.5.2 – Advanced ICT for Risk assessment and Patient Safety Advanced computerised adverse event systems: Identification of common patterns in safety-relevant events beyond reporting nosocomial infections and/or Adverse Drug Events (ADE). New tools for prediction, detection and monitoring of adverse events and other relevant information. Based on innovative data mining and integration techniques of existing databases and specific applications. Emerging technologies like semantic mining should be explored through multimedia databases. Include validation leading to quantitative benefits. FP7 Objective ICT 2007.5.2 – Advanced ICT for Risk assessment and Patient Safety:  FP7 Objective ICT 2007.5.2 – Advanced ICT for Risk assessment and Patient Safety One CSA - New risk prediction for large scale local, regional or even global adverse health events (infectious outbursts, bioterrorism): new risk prediction, assessment and management tools for preparation, surveillance, support and intervention in case of large adverse health events. FP7 Objective ICT 2007.5.2 – Advanced ICT for Risk assessment and Patient Safety:  FP7 Objective ICT 2007.5.2 – Advanced ICT for Risk assessment and Patient Safety When : Call 1 Instruments: Advanced computerised adverse event systems: Collaborative projects (CPs) New risk prediction for large scale events: Coordination and Support Actions (CSAs) Virtual Physiological Human:  Virtual Physiological Human Concept basis Basis is the International physiome project www.physiome.org Computational frameworks and ICT-based tools for multiscale models of the human anatomy, physiology and pathology Libraries of data and toolbox for simulation and visualisation Patient specific model from biosignals and images including molecular images Virtual Physiological Human:  Virtual Physiological Human VPH to model & simulate human physiology and disease-related processes - key facilitator for: Personalised (Patient-specific) healthcare solution Early diagnostics & Predictive medicine Virtual Physiological Human:  Virtual Physiological Human FP6 - Projects related to VPH: Continuation from Bio-Medical Informatics and healthGrid projects (FP6 – Call 4) out of which: Immunogrid (immune system physiology –www.immunogrid.org) @Neurist (neurovascular pathology – www.aneurist.org) LHDL (musculoskeletal system physiology – www.livinghuman.org) Roadmaps STEP (Strategy for the Europhysiome – www.europhysiome.org) SHARE (Supporting HealthGrid activities & research in Europe – www.eu-share.org) FP7 Objective ICT 2007.5.3 – Virtual Physiological Human:  FP7 Objective ICT 2007.5.3 – Virtual Physiological Human Technical focus on: Patient-specific modelling and simulation Target: molecular, cell, tissue, organs or systems Modelling & simulation of organs/systems targeting specific clinical needs. Go beyond the state of art of available models Models should be multilevel when appropriate Better understanding of the functioning of the organs New insight into the response to physiological changes FP7 Objective ICT 2007.5.3 – Virtual Physiological Human:  FP7 Objective ICT 2007.5.3 – Virtual Physiological Human Technical focus on: Data integration and knowledge extraction Target: creation and formalisation of patient specific knowledge from multi-level integration of biomedical data Requirement: open distributed health infrastructures and tools Focus: Coupling scientific research data with clinical/empirical databases Linking genotype data (genetic markers, pathways) with phenotype data (clinical data) Image processing assessing disease evolution/presence Data mining and image processing across many biological levels FP7 Objective ICT 2007.5.3 – Virtual Physiological Human:  FP7 Objective ICT 2007.5.3 – Virtual Physiological Human Technical focus on: Patient-specific modelling and simulation & b) Data integration and knowledge extraction to be demonstrated on c) following clinical applications: Medical simulation environments for surgery Environment used for simulation, training and planning of surgeries Prediction of disease or early diagnosis (patient specific) knowledge and predisposition obtained from lab tests, biomedical imaging (imaging bio-markers and other data) assessment of efficacy/safety of drugs Use patient specific computational models to assess the drugs. Alternative screening for clinical trials FP7 Objective ICT 2007.5.3 – Virtual Physiological Human:  FP7 Objective ICT 2007.5.3 – Virtual Physiological Human Integrating action (NoE): in multilevel modelling and simulation of human physiology sharing of knowledge multidisciplinary training programmes reusable software tools Coordination & Support Actions Enhancing security and privacy in modelling and simulation addressing patient data processed over distributed networks use of genetic data Trustworthy environment International cooperation on health information systems based on Grid capabilities FP7 Objective ICT 2007.5.3 – Virtual Physiological Human:  FP7 Objective ICT 2007.5.3 – Virtual Physiological Human When : Call 2 Instruments: (a-c) CPs (d) Integrating action: NoE (e) Coordination & Support Actions: CSAs Consultation information:  Consultation information Personal Health Systems for Monitoring and Point-of-Care diagnostics Consultation workshop on “Personal Health Systems: the path from FP6 to FP7”, Luzern, 2nd February 2006. Report available at: http://europa.eu.int/information_society/activities/health/docs/events/phealth2006/fp7phs_consultation_workshop_final-report.pdf pHealth 2006, International workshop on wearable micro- and nanosystems for personalised health, Luzern, Switzerland, January 2006 (http://www.phealth-2006.com) Virtual Physiological Human VPH white paper (Nov 2005): http://europa.eu.int/information_society/activities/health/docs/events/barcelona2005/ec-vph-white-paper2005nov.pdf 2nd (STEP) white paper for the VPH research roadmap (2006): http://www.europhysiome.org 2006 Conference on “ICT for BIO-medical sciences”: http://europa.eu.int/information_society/events/ict_bio_2006/index_en.htm Consultation information :  Consultation information Advanced ICT for Risk Assessment and Patient Safety 2nd of June 2004 – workshop on ICT for Patient safety (report provided by Deloitte & Touche) Benefits of ICT for patient safety - A strategic seminar at "eHealth 2006“ (High Level Conference. Malaga, 10-12 May 2006) http://www.ehealthconference2006.org Expert meeting on "Impact of Emerging ICT on Patient Safety" at "ICT for Bio-Medical Sciences 2006“, 30 June 2006, Brussels http://europa.eu.int/information_society/events/ict_bio_2006/satellite-events/index_en.htm Patient safety workshop in Geneva during the World of Health IT Conference, 10 October 2006 http://www.worldofhealthit.org/education/edu_Programme.asp#partner_mtg Contact persons :  Contact persons DG INFSO Unit H1 – “ICT for Health” Personal Health Systems for Monitoring and Point-of-Care diagnostics – Rainer Guenzler - Loukianos Gatzoulis Advanced ICT for Risk Assessment and Patient Safety - Octavian Purcarea Virtual Physiological Human – Alessandra Martini – Jean- Marie Auger - Joël Bacquet Emails: firstname.surname@ec.europa.eu Why do it?:  Why do it? Technological Innovation:  Technological Innovation Phase 1 Research and Develop Phase 2 Market preparation Phase 3 Commence Business Phase 4 Profit IPR Funding Fundamentals:  Funding Fundamentals Innovative Projects 50% support (75% if you are Academic/SME/etc) The Commission give you ‘half’ of what you spend Involving Partners from Multiple Countries At least 3 In Topics identified by The Commission’s Workprogramme In response to specific calls for Proposals By means of a Contract with The European Commission Co-Financing:  Co-Financing 4 Equal Participants Equal rights of access Exploitation strategy is Essential:  Exploitation strategy is Essential Finding Partners:  Finding Partners CORDIS Partner Finding Service Do it Yourself http://partners-service.cordis.lu/ Hang around in foreign bars IDEAL*IST Partner Finding Service Free – assisted service UK Contact Singleimage http://www.singleimage.co.uk/PartnerSearch/idealist.htm 44 1480 497712 Framework 6 2000-2004:  Framework 6 2000-2004 1140 Projects 3.83 B€ 13779 Partners from 80 Countries UK 1456 Contractors In 669 Projects UK Grant 397.8 M€ ( ~ 275 M£ ) Total Cost of these Projects 4 B€ ( ~2.8 B£) FP6 had six main Calls:  FP6 had six main Calls Call Networking:  Networking Networking With The Commission before the call Networking To find candidate partners Networking With your partners Networking With The Commission during your project Networking With your fellow projects Bigger stronger networks generating NEW opportunities FP6UK Information Society Support The UK’s Information Society National Contact Point:  FP6UK Information Society Support The UK’s Information Society National Contact Point Advice, Support & e-Mails Access by one of the following: http://fp6uk.ost.gov.uk/ist 0870 191 0112 is@fp6uk.co.uk This FREE service is made available through funding from DTI

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