periapical response

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Information about periapical response
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Published on November 16, 2008

Author: clinicaomega

Source: authorstream.com

Slide 1: Pulpal and periapical immune responsesto infection Slide 2: There is no evidence that necrotic pulp tissue per se can elicit periapical inflammation, in the absence of bacteria. Slide 3: 78 monkey teeth with aseptically necrotized pulps 26 bacteria-free 52 bacteria infected 7 months Apical periodontitis No apical inflammation Moller & Fabricius 1981 Slide 4: Periapical responses to pulpal infection Slide 5: Bacterial products IL-1 IL-2 MF Th B Periapical inflammation and bone destruction MHC-II IL-1, IL-6 TNF╬▒ PGE Ag Periradicular lesions - barrier : products Microbial Periradicular lesions - barrier Complement Granulomatous tissue Defence elements PMNs Microorganisms Very few endodontopathogens can advance through the barrier. Extraradicular microorganisms : Abscessed AP Actinomyces spp, Propionibacterium propionicum Infected radicular cysts Infected material displaced into the periapical tissues Extraradicular microorganisms Possible factor in the failure of the endodontic therapy.

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