Oral Mucositis in Cancer Patients

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Information about Oral Mucositis in Cancer Patients
Health & Medicine

Published on October 2, 2014

Author: BrianFrenzel

Source: slideshare.net

Description

A leader in the biopharmaceutical field, Brian Frenzel has worked extensively in drug product and business development. Brian Frenzel currently serves as president and CEO of Tosk, Inc., a company that works to develop products to alleviate the side effects of cancer treatments, such as mucositis.

1.  A leader in the biopharmaceutical field, Brian Frenzel has worked extensively in drug product and business development. Brian Frenzel currently serves as president and CEO of Tosk, Inc., a company that works to develop products to alleviate the side effects of cancer treatments, such as mucositis. Mucositis is a condition that affects the mucosal lining of the body’s gastrointestinal tract. A number of cancer treatments can cause mucositis, which can result in inflammation, painful ulcers, and opening a route of infection from the GI tract into the bloodstream.

2.  While mucositis can occur throughout the gastrointestinal tract, it is particularly common in the oral mucosa, the mucosal tissue in the oral cavity. The mouth, tongue, gums, and throat are particularly sensitive areas that are prone to damage by radiation and chemotherapy. A patient suffering from oral mucositis often develops painful open sores in the mouth. These sores make it difficult to eat and can lead to a cycle of infection and further damage to oral tissues. Similar damage can occur in other GI tissues, including the stomach, intestinal tract, and anal cavity.

3.  The pain and loss of weight associated with mucositis often lead physicians to limit dosing of chemotherapy and radiation therapy. Consequently, mucositis not only results in reduced quality of life for cancer patients, but can also reduce the effectiveness of the cancer treatment itself. Consequently, efforts to develop drugs to block chemotherapy and radiation therapy induced mucositis are vitally important to improving outcomes for cancer patients.

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