How Decoding Our Genetic Secrets Can Save Our LivesHow Decoding Our Genetic Secrets Can Save Our Lives

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Information about How Decoding Our Genetic Secrets Can Save Our LivesHow Decoding Our...

Published on March 10, 2009

Author: hongiiv

Source: slideshare.net

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From: Google Backs Harvard Scientist's 100,000-Genome Quest (Update2) -Bloomberg (http://www.bloomberg.com/apps/news?pid=newsarchive&sid=a9FTNggspOLs)
How Decoding Our Genetic Secrets Can Save Our Lives, 맞춤의료와 예방의학에 활용되는 유전체 해독

How Decoding Our Genetic Secrets Can Save Our Lives How analyzing genes can indicate health risks and arm a person to take preventive measures. As the genetic mapping BRCA1 gene is A woman with a mutated BRCA1 In some people, there is an hereditary a tumor- process becomes more gene has a 60-80% chance of gene mutation blocking the tumor- suppressor. developing breast cancer and a suppressing function. (A gene is made affordable, 20-30% chance of ovarian cancer in up of “bases” represented by letters) Chromosome 17 understandable her life and men have an increased A normal BRCA1 sequence risk of prostate cancer. and available, AAA ARC TTA GAG TCT people will have An hereditary mutation that deletes Mutated BRCA1 increased two bases in the sequence... sequence GA information about AAA ATC TTA __G TCT BRCA 1 their hereditary gene ...makes the rest of the bases shift predispositions. to the two empty spots. AAA ATC TTA GTC TCC Offspring of those with this mutation have a Mutated 50% risk of inheriting BRCA1 sequence Source: George Church, Havard the mutated gene. University; Mayo Clinic; National Cancer Institute Jessica Chosid - Bloomberg What a person Avoiding risk Preventive Preventive surgery Surveillance can do if they By exercise and chemotherapy Mastectomy or To detect cancer as soon Center for Genome Science have the limiting alcohol Drug therapy such removal of fallopian as possible http://cgs.cdc.go.kr mutated gene: comsumption as Tamoxifen tubes and ovaries

? BRCA1 - BRCA1 .( , “ ” .) 17 BRCA1 AAA ARC TTA GAG TCT , BRCA1 A BRCA 1 G AAA ATC TTA __G TCT . AAA ATC TTA GTC TCC 50% . Source: George Church, Havard BRCA1 University; Mayo Clinic; National Cancer Institute Jessica Chosid - Bloomberg Center for Genome Science http://cgs.cdc.go.kr ?

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