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Published on October 21, 2007

Author: Jolene

Source: authorstream.com

Overview of Arboviruses in the United States:  Overview of Arboviruses in the United States John A Burns School of Medicine University of Hawaii at Manoa, Honolulu, Duane J Gubler, ScD Director Slide2:  Arbovirus Arthropod-borne virus 534 Registered Arboviruses Slide4:  Zoonosis A pathogen of animals transmissible to humans under natural conditions. n [Gk zo- animal + nosos disease] Slide5:  Climate, weather, Environmental factors Slide6:  BF - Barmah Forest MAY - Mayaro VEE - Venezuelan Equine Encephalitis CE - California Encephalitis MVE - Murray Valley Encephalitis WEE - Western Equine Encephalitis Chik - Chikungunya ONN – O’nyong-nyong WN - West Nile CCHF - Congo-Crimean Hemorrhagic Fever ORO - Oropouche WSL - Wesselsbron DEN - Dengue RVF - Rift Valley Fever YF - Yellow Fever EEE - Eastern Equine Encephalitis RR - Ross River JE - Japanese Encephalitis SLE - St. Louis Encephalitis KFD - Kyasanur Forest Disease SIN - Sinbis LAC - LaCrosse Encephalitis TBE- Tick-Borne Encephalitis DEN DEN DEN DEN DEN DEN DEN DEN DEN DEN DEN CHIKDEN DEN DEN DEN DEN DEN DEN DEN DEN DEN JE JE JE JE JE JE CHIK CHIK CHIK CCHF CCHF CCHF CCHF MVE RR BF SIN SIN TBE TBE CE WN WN WN WN WN WN WN WN WN WN WSL ONN RVF RVF RVF RVF KFD YF YF YF YF YF ORO ORO ORO MAY VEE VEE VEE EEE LAC SLE Global Re-emergence of Epidemic Arboviral Diseases 1990-2006 WN WN WN EEE SLE WN WN WN DEN DEN DEN DEN DEN DEN WN WN WN Arboviruses in the United States Selected representatives by Family:  Arboviruses in the United States Selected representatives by Family *not endemic PRIMARY ARBOVIRUSES AFFECTING HUMANS IN THE U.S.:  PRIMARY ARBOVIRUSES AFFECTING HUMANS IN THE U.S. Eastern Equine Encephalitis Western Equine Encephalitis La Crosse Saint Louis Encephalitis West Nile Dengue Fever Slide9:  Eastern Equine Encephalitis Human cases: 1964-2005 Human Cases Reported from 20 States Eastern Equine Encephalitis Total Cases in U.S. 1964-2006:  Eastern Equine Encephalitis Total Cases in U.S. 1964-2006 Year Number of Cases Reported Human Cases Average = 5/year; Range = 0-21 Slide11:  Western Equine Encephalitis Human cases: 1964-2005 Human Cases Reported from 21 States Western Equine Encephalitis Total Cases in U.S. 1964-2006:  Western Equine Encephalitis Total Cases in U.S. 1964-2006 Year Number of Cases Reported Human Cases Average = 15/year; Range = 0-172 Slide13:  La Crosse Encephalitis Human cases: 1964-2005 Human Cases Reported from 30 States La Crosse Encephalitis Total Cases in U.S. 1964-2006:  La Crosse Encephalitis Total Cases in U.S. 1964-2006 Year Number of Cases Reported Human Cases Average = 80/year; Range = 29-167 Slide15:  St. Louis Encephalitis Human cases: 1964-2005 Human Cases Reported from 43 States St. Louis Encephalitis Total Cases in U.S. 1964-2006:  St. Louis Encephalitis Total Cases in U.S. 1964-2006 Year Number of Cases (log scale) Reported Human Cases Average = 111/yr; Range = 2-1967 Slide17:  West Nile Human cases: 1999- 2005 Human Cases Reported from 46 States Epidemic West Nile Virus in the United States, 1999-2006:  Epidemic West Nile Virus in the United States, 1999-2006 * Reported as of 5/1//2007 There is no reason to believe that West Nile virus will be the last exotic arbovirus to be introduced into the U.S.:  There is no reason to believe that West Nile virus will be the last exotic arbovirus to be introduced into the U.S. Exotic Infectious Diseases That Have Recently Been Introduced to the US:  Exotic Infectious Diseases That Have Recently Been Introduced to the US West Nile Fever Yellow Fever Mayaro Fever Dengue Fever Chikungunya SARS Influenza Lassa Fever Monkeypox CJD/BSE HIV/AIDS Cholera E. coli O157 Malaria Leishmaniasis Chagas Disease Cyclospora Exotic Mosquito Species Recently Introduced and Established in the US:  Exotic Mosquito Species Recently Introduced and Established in the US Aedes (Stegomyia) albopictus Ochlerotatus (Aedes Finlaya) togoi Ochlerotatus (Aedes Finlaya) japonicus Aedes bahamensis Culex biscayensis Global Threat of Epidemic Arboviral Diseases Challenge to Reverse the Trend:  Global Threat of Epidemic Arboviral Diseases Challenge to Reverse the Trend Movement of Pathogens and Vectors via Modern Transportation Lack of Effective Laboratory-based Surveillance Lack of Public Health Infrastructure to Prevent & control Vector-borne and Zoonotic Diseases Trained personnel Laboratory capacity Tools (vaccines, drugs, insecticides, etc) Understanding disease ecology Political Will Economic support

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