Gettenberg Identifying DNA as the Genetic Material

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Published on March 5, 2014

Author: mgettenberg

Source: slideshare.net

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Identifying DNA as the Genetic Material

8.1 Identifying DNA as the Genetic Material KEY CONCEPT DNA was identified as the genetic material through a series of experiments.

8.1 Identifying DNA as the Genetic Material Griffith finds a ‘transforming principle.’ • Griffith experimented with the bacteria that cause pneumonia. • He used two forms: the S form (deadly) and the R form (not deadly). • A transforming material passed from dead S bacteria to live R bacteria, making them deadly.

8.1 Identifying DNA as the Genetic Material Avery identified DNA as the transforming principle. • Avery isolated and purified Griffith’s transforming principle. • Avery performed three tests on the transforming principle. – Qualitative tests showed DNA was present. – Chemical tests showed the chemical makeup matched that of DNA. – Enzyme tests showed only DNA-degrading enzymes stopped transformation.

8.1 Identifying DNA as the Genetic Material Hershey and Chase confirm that DNA is the genetic material. • Hershey and Chase studied viruses that infect bacteria, or bacteriophages. – They tagged viral DNA with radioactive phosphorus. – They tagged viral proteins with radioactive sulfur. • Tagged DNA was found inside the bacteria; tagged proteins were not.

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