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Gentegra Ambient Stabilization Technologies for DNA RNA 3 3_14

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Information about Gentegra Ambient Stabilization Technologies for DNA RNA 3 3_14
Technology

Published on March 4, 2014

Author: rbjamieson

Source: slideshare.net

Description

GenTegra produces and markets solutions for stabilizing DNA and RNA in solution, or dried down for long term storage at ambient temperatures, along with bio-banking products for whole blood stabilization and long-term room temperature storage. For instance, our customers add GenTegra RNA immediately upon purifying the RNA and it protects while in liquid form. Once they are done with the sample, they dry it down and the RNA is protected for years. It can be reconstituted for re-sampling, dried down again and re-stored up to 7 times. And it does not require purification as the product is small-molecule based; nothing in the product will interfere with any downstream analysis.

See our website at Gentegra.com for more information or
contact us for a seminar at 925-461-3010.
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LLC Redefining Ambient Stabilization February 2014 1 | Proprietary and GenTegra Confidential | 2/11/2014

As a researcher, the value of your results is our most important priority. Allowing you to protect your biosamples, from the earliest stage possible, through long-term storage is what we offer. RNA can be protected immediately after being isolated and purified, through short and long term storage. DNA can be protected either without purification for biobanking, or as purified for transport and storage. 2 | Proprietary and GenTegra Confidential | 2/11/2014

Product Overview GenTegra DNA & GenTegra RNA product lines Stabilization and storage of purified/extracted DNA & RNA GenPlates & Archives High density stabilization and storage of blood & biosamples GenSolve High yield recovery of stored blood and biosamples on FTA paper 3 | Proprietary and GenTegra Confidential | 2/11/2014

Products GenTegra-RNA • Immediate and long-term protection of RNA GenTegra-DNA • Long-Term protection of DNA GenTegra is the only truly DRY state storage method available, providing a better and more risk free storage. 4 | Proprietary and GenTegra Confidential | 2/11/2014

GenTegra-RNA RNA: unstable as it is being purified GenTegra-RNA: immediate protection for the RNA while being processed When dried the RNA is given long term protection at ambient temperature Target users: Epigenomics, Proteomics Targeted sequencing, NGS in general, Cancer genetics, etc. 5 | Proprietary and GenTegra Confidential | 2/11/2014

GenTegra-DNA DNA is more stable than RNA and is relatively safe in liquid for normal processing times. GenTegra-DNA provides long-term stabilization of the DNA when the solution is dried and stored at ambient temperature with data for 9 years of storage and accelerated data equivalent to 30 years. Target users: NGS in general epigenomics targeted sequencing cancer genetics etc. 6 | Proprietary and GenTegra Confidential | 2/11/2014

Products GenPlates • Long-term, high density storage of blood, blood products and biosamples GenSolve • High yield extraction of biosamples from FTA and other paper Archive cabinets • High density dry GenPlate storage at ambient temperature 7 | Proprietary and GenTegra Confidential | 2/11/2014

GenPlates & GenSolve Products GenPlates • High density method of storing blood (and biologicals) of FTA paper • Universally accepted FTA disc of 6 mm diameter • Guthrie cards, other papers • GenTegra offers 5 configurations for user; 1, 3, 6, 12, 24 regions • All in a 384 half-height SBS microplate • Really a choice of how many replicates the user needs/wants Target Markets • • • • Small genome project (State of Alaska Salmon project) Targeted human studies Species projects for endangered animals Ag and vet studies 8 | Proprietary and GenTegra Confidential | 2/11/2014

GenPlates 1 Region, 384 elements 3 Region, 96 elements 6 Region, 40 elements 12 Region, 16 elements 24 Region, 4 elements 9 | Proprietary and GenTegra Confidential | 2/11/2014 Every GenPlate is barcoded and hermetically sealed in a silvered mylar bag. GenPlates shelf life is essentially unlimited before opening and decades after opening if properly stored in low humidity environment.

GenTegra Products Personal Archive cabinet • • • • High density convenient GenPlate storage at ambient temperature Holds 1176 GenPlates or half that number of standard microplates Dehumidifier and Barcode scanner included GenConnect software for sample tracking, optional 10 | Proprietary and GenTegra Confidential | 2/11/2014

Products GenSolve • • • • High yield extraction of biosamples from FTA and other paper No commercial competitive product Generic protocols for DO-IT-YOURSELF GenSolve significantly improves quantity of extracted DNA 11 | Proprietary and GenTegra Confidential | 2/11/2014

Redefining Ambient Stabilization 12 | Proprietary and GenTegra Confidential | 2/11/2014

LLC Contacts: James Nelson, PhD Bruce Jamieson +1 925-461-3010 +1 408-813-2344 JamesN@gentegra.com BruceJ@gentegra.com www.gentegra.com 13 | Proprietary and GenTegra Confidential | 2/11/2014

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