gel manufacturing

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Information about gel manufacturing

Published on December 23, 2011

Author: vhbhaskar


GEL PREPARATION : GEL PREPARATION Presented By : Mr. Naresh Rajgor, Assistant Professor, M.P. Patel College of Pharmacy, Kapadwanj GELS: GELS Gels are aqueous colloidal suspensions of the hydrated forms of insoluble medicaments. In gels hydrated threads or granules of the disperse phase are infinitely associated with the dispersion medium. Gels contain polymer less than 10% and they may be clear to turbid depending upon aggregation formation of polymer. The gels forming polymers are Natural Polymers like tragacanth, pectin, agar, carrageen, alginic acid, gelatin. Synthetic & semi synthetic Polymers like Methyl Cellulose, HMC, Carbopols , CMC. Fluid phase may be water or water miscible organic solvents. Evaporation of the water produces a pleasant cooling. FORMULATION: FORMULATION Sr. No. Formulating Agents Example of the agents 1 Medicaments Local anaesthetics , Spermicides , Antiseptic, Vasoconstrictors. 2. Gelling Agents Tragacanth, Sodium alginate, pectin, Starch, Gelatin, Carbomer , PVA, Clays, Bentonite , M.C., CMC, HPMC 3. Prevervatives Methylhydroxy benzoate-0.2 %, Propyl hydroxy Benzoate -0.05% Chlorocresol -0.1% Benzal Konium Chloride - 0.2% 4. Other Additives- To prevent Dehydration Glycerol, Propylene Glycol, Sorbitol 5. Chelating Agents EDTA Container: Collapsible Tube Storage: Well Closed, store in a cool place

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