FundingBiomedicalRes earchpresentedbyDeni sBaylor

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Published on October 16, 2007

Author: Irvette

Source: authorstream.com

FUNDING BIOMEDICAL RESEARCH Presented by Denis Baylor Senior Scientific Officer, Howard Hughes Medical Institute December 6, 2004 :  All text is Arial Presentation Title: Bold, 24/29, 16 before; White, All Caps Presented by: 10/14, 33 before, White Name: 24/30, 4 before Presenter Title: 14/17 0 before Date: 14/17, 8 before FUNDING BIOMEDICAL RESEARCH Presented by Denis Baylor Senior Scientific Officer, Howard Hughes Medical Institute December 6, 2004 QUICK FACTS ABOUT HHMI:  QUICK FACTS ABOUT HHMI Largest non-government funder of biomedical research in US $700 M Annual budget supports: 301 HHMI Investigators – 68 in California 135 International scholars 20 HHMI professors Undergraduate teaching Graduate, medical student programs Heading: 24/29 ALL CAPS, bold, COLOR: 0C,2M,18Y,52K BULLET TEXT: 24/27, 19 before Sub-bullet text and the next level are both 16/23, 0 before Best way to get new sub-bullets, etc., is to copy-paste and type over the old text. All Heads are from top left: hz: 0.59” vt: 0.17” anchor: middle Text box Position From top left corner: hz: .58” vt: 1.4’ anchor: top Photo: © Kathleen Dooher for HHMI HHMI INVESTIGATORS: MEASURES OF DISTINCTION:  HHMI INVESTIGATORS: MEASURES OF DISTINCTION Heading: 24/29 ALL CAPS, bold, COLOR: 0C,2M,18Y,52K BULLET TEXT: 24/27, 19 before Sub-bullet text and the next level are both 16/23, 0 before Best way to get new sub-bullets, etc., is to copy-paste and type over the old text. All Heads are from top left: hz: 0.59” vt: 0.17” anchor: middle Text box Position From top left corner: hz: .58” vt: 1.4’ anchor: top 301 Investigators include: 10 active Nobel Laureates >100 members NAS This year: 2 Nobel prize winners – Buck, Axel 11 elected to NAS in total class of 29 in biomedical sciences NEW HHMI INITIATIVE: JANELIA FARM RESEARCH CAMPUS:  NEW HHMI INITIATIVE: JANELIA FARM RESEARCH CAMPUS Opens Summer 2006 in Rural Virginia Focus: Neural Circuits New physical and computational tools for imaging tissues, cells, molecules Will have 180 full-time scientists Currently recruiting Emphasis on collaboration, interdisciplinary research Heading: 24/29 ALL CAPS, bold, COLOR: 0C,2M,18Y,52K BULLET TEXT: 24/27, 19 before Sub-bullet text and the next level are both 16/23, 0 before Best way to get new sub-bullets, etc., is to copy-paste and type over the old text. All Heads are from top left: hz: 0.59” vt: 0.17” anchor: middle Text box Position From top left corner: hz: .58” vt: 1.4’ anchor: top SELECTING WHO TO FUND:  SELECTING WHO TO FUND Heading: 24/29 ALL CAPS, bold, COLOR: 0C,2M,18Y,52K BULLET TEXT: 24/27, 19 before Sub-bullet text and the next level are both 16/23, 0 before Best way to get new sub-bullets, etc., is to copy-paste and type over the old text. All Heads are from top left: hz: 0.59” vt: 0.17” anchor: middle Text box Position From top left corner: hz: .58” vt: 1.4’ anchor: top HHMI supports people not projects Identify outstanding individuals, let them follow their instincts Ego involvement and passion are keys to scientific discovery CSCI will support projects, but people important: people and projects Support promising young scientists as well as established seniors SELECTING WHAT TO FUND:  SELECTING WHAT TO FUND Heading: 24/29 ALL CAPS, bold, COLOR: 0C,2M,18Y,52K BULLET TEXT: 24/27, 19 before Sub-bullet text and the next level are both 16/23, 0 before Best way to get new sub-bullets, etc., is to copy-paste and type over the old text. All Heads are from top left: hz: 0.59” vt: 0.17” anchor: middle Text box Position From top left corner: hz: .58” vt: 1.4’ anchor: top Support work with potential to have high impact Reward risk-taking Support broad range of approaches: difficult to predict where next great advance will come Support collaborative, interdisciplinary research Strong principle at Janelia Farm – CSCI also? SELECTION PROCESS:  SELECTION PROCESS Heading: 24/29 ALL CAPS, bold, COLOR: 0C,2M,18Y,52K BULLET TEXT: 24/27, 19 before Sub-bullet text and the next level are both 16/23, 0 before Best way to get new sub-bullets, etc., is to copy-paste and type over the old text. All Heads are from top left: hz: 0.59” vt: 0.17” anchor: middle Text box Position From top left corner: hz: .58” vt: 1.4’ anchor: top Make selection process apolitical, rigorous Investigator competitions: peer review by outside panel of recognized experts Avoid conflicts of interest: personal, institutional, commercial Electronic submission of application materials (saves time, trees) RESEARCH MANAGEMENT:  RESEARCH MANAGEMENT Heading: 24/29 ALL CAPS, bold, COLOR: 0C,2M,18Y,52K BULLET TEXT: 24/27, 19 before Sub-bullet text and the next level are both 16/23, 0 before Best way to get new sub-bullets, etc., is to copy-paste and type over the old text. All Heads are from top left: hz: 0.59” vt: 0.17” anchor: middle Text box Position From top left corner: hz: .58” vt: 1.4’ anchor: top Minimize paperwork and micromanagement Allow flexible use of budgeted funds State-of-the-art equipment and physical facilities Promote sharing ideas, results by meetings, workshops Software, reagents, transgenic animals, databases should be shared. Should CSCI require sharing as a condition for support? Commercial interests should not dictate course or reported outcomes of research REVIEWING PROCESS – SHOULD FUNDING CONTINUE?:  REVIEWING PROCESS – SHOULD FUNDING CONTINUE? Heading: 24/29 ALL CAPS, bold, COLOR: 0C,2M,18Y,52K BULLET TEXT: 24/27, 19 before Sub-bullet text and the next level are both 16/23, 0 before Best way to get new sub-bullets, etc., is to copy-paste and type over the old text. All Heads are from top left: hz: 0.59” vt: 0.17” anchor: middle Text box Position From top left corner: hz: .58” vt: 1.4’ anchor: top Rigorous review of progress at 5 year intervals Peer review by outside panel of experts Avoid personal, commercial, conflicts of interest in review Reviewers evaluate progress over past funding period, assess plans for next. The “deletion test” Funding the best science sometimes dictates not continuing support

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