Fluoroquinolonas

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Information about Fluoroquinolonas
Health & Medicine

Published on March 13, 2014

Author: kdcloop

Source: slideshare.net

Nombres: David Rodríguez Cely Erika Natalia Romero Molina Daniel Sebastián Parra González Mónica Montaño

Fluoroquinolonas Tipo de Inhibidor: Es un inhibidor que actúa en sitios de unión alostérica. Uso: Para infecciones resistentes a antibióticos de primera línea, su uso es como antibacteriano. Su uso es principalmente en infecciones genitourinarias y problemas de sepsis severos. Así mismo en algunos casos como profilácticos. Mecanismo de acción: Se une reversiblemente a la subunidad A de la DNA girasa (topoisomerasa II), impidiendo la correcta formación de la horquilla de replicación del DNA. Las fluoroquinolonas son quinolonas de segunda generación.

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