Fermenta biotech Ltd - Company & Product

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Information about Fermenta biotech Ltd - Company & Product
Business & Mgmt

Published on February 19, 2014

Author: fermentabiotech1

Source: slideshare.net


Fermenta Biotech Ltd (FBL), incepted under the auspices of Duphar Interfran Ltd (now known as DIL Ltd.), is the brainchild of late Mr. Vasant Kumar Datla. Established in 1986, FBL pioneered the manufacture of Penicillin G Amidase enzyme in India; it emerged as the leader in enzyme technologies for beta lactams (β-lactams) synthesis.

FBL manufactures Vitamin D3 (Cholecalciferol) (the only manufacturer and supplier in India and among the top few manufacturers in the world) and constantly looks for value addition. FBL manufactures Cholecalciferol also know as Vitamin D3 for further applications in global pharmaceutical, food, veterinary and feed industries (premix); cholecalciferol solutions for use in human food supplements; Vitamin D3 resin in oil and Vitamin D3 500 feed grade for use in animal feed supplements; and activated dimethicone powder (Silicon Powder) for antiflatulent use.
From a pioneer of Penicillin G Amidase (PGA), FBL commercialised new and improved Novel Penicillin G Acylase (NPGA) for the synthesis of Amoxicillin, Cephalexin and developed platform for other Cephalasporins (Cefaclor, Cephadroxil etc). FBL also offers superior Candida antarctica lipase B or CAL B Lipase in both immobilized and free enzyme for various applications ranging from Chiral chemistry to Biofuel (Green Chemistry). FBL offers proprietery immobilization platform, DILBEADS for immobilized enzyme development.

FBL provides customized environmental biotech solutions through consultancy, supply of suitable biotech products and services in three segments – sewage treatment plant (STP), lake and pond remediation and oil sludge remediation.

Today FBL has become a multifaceted organization with a high degree of focus on research, development and product delivery in the field of biotechnology, pharmaceutical and environmental solutions

Fermenta Biotech Limited Fermenta Biotech Ltd.

DIL Group – Genesis and Business Tree Founder - Late Dr. D.V.K. Raju PhD, UK 1953 : Biological Evans Ltd. (now Biological E Ltd.) 1951: International Franchisees Ltd. Toll mfg – Pharma & Cosmetic Industry 1969 : Uni-Sankyo Ltd. (first Indo-Japanese JV) 1963 : JV with Philips Duphar name changed to Duphar Interfran Ltd Manufacturing and Marketing of Pharmaceutical Products 1976 - Listed on Bombay Stock Exchange Fermenta Biotech Ltd. 1980 : Duphar taken over by Solvay Solvay Pharmaceutical becomes our JV Partner 1986 - Founded Fermenta Biotech Ltd 1999-2002 : Demerger of Pharma Business in favor of Solvay Solvay Pharmaceutical becomes our premier client Name changed to DIL Ltd.

Business Divisions FBL business activities are divided into 3 major focus areas, each supported by a research based approach. APIs: Niche products with value addition. e.g. Vitamin D3 and Phenyramidol Biotech: Novel Enzyme products for pharmaceutical and fine chemical industry. e.g. Enzyme for antibiotic synthesis. Environmental Life sciences: Products and services for various environmental solutions. e.g. Sewage treatment / lake bioremediation / Oil sludge remediation. Fermenta Biotech Ltd. APIs Biotech Environmental Life Sciences

Overview • Core area of Business API’s, Intermediates & Biotechnology Products • Incorporation July, 1986 • Manufacturing facilities 1) Kullu - Himachal Pradesh (North of India) 2) Dahej - Gujarat (West of India) • Regulatory compliances cGMP compliant facility • Manpower Qualified & experienced pool of 200 personnel, which will become 300 by end of this year • Head Office : Thane (Mumbai) Fermenta Biotech Ltd.

Locations FBL Factory Kullu FBL Factory Dahej FBL HO Mumbai Fermenta Biotech Ltd.

Vitamin D3 Cholecalciferol (Vitamin D3 crystalline) CAS No. : 67-97-0 Each gram contains 40 million IU of Vitamin D3 Certifications EDQM (COS) FAMI QS Halal Kosher WHO-GMP HACCP ISO 9001: 2008 ISO 14001: 2004 Regulatory Submissions: US DMF filed Canadian DMF Filed Pharmacopeias: Matches EP, USP, FCC & IP Fermenta Biotech Ltd.

FBL Vitamin D3 Introduction • Only Manufacturer in India, among top 3 producers worldwide • Manufacturing for more than four decades • Obtained Technology from Solvay Pharmaceuticals, Netherlands • Supplying to more than 200 customers both Domestic and International. • More than 90% market share in the Indian market. Fermenta Biotech Ltd.

Vitamin D3 40 MIU • Glass Ampoules: – Packing in 10gm/100gm Glass ampoules under vacuum Packing in 250gm /1Kg Aluminum containers under Argon Gas 1 Kg 250 gm Fermenta Biotech Ltd.

VITADEE Vitamin D3 100 CWD • Vitamin D3 100 CWD variants VITADEE CWD /DS and VITADEE CWD / MS grades • Each gram of product contains 100,000 IU/g of Vitamin D3. • Used in food / nutraceutical applications • Product forms uniform dispersion in water. • Aligned towards the products most commonly used currently by the industry • Product complies Ph. Eur. and DMF to be available soon Fermenta Biotech Ltd.

Cholecalciferol Solution 1MIU Ph.Eur / USP • Available in strengths of 1 MIU / gm or 4 MIU / gm • Used in food / nutraceutical applications • Available in corn oil / Arachis oil as base • Packed in 1 kg / 0 kg aluminium containers. Fermenta Biotech Ltd.

Vitamin D3 Resin Oily feed grade • Available in 2 / 4/ 5/ 10 / 15 MIU gm concentrations • Used for animal feed premix / blends manufacturing • Available in soyabean / sunflower oil as base • Packed in 1 kg / 10 Kg aluminium containers Fermenta Biotech Ltd.

Vitamin D3 500 Feed Grade Powder (500,000 IU/gm) • Available as white – yellowish free flowing powder with strength of 500,000 IU /gm • Used for animal feed, dry blends manufacturing • Packed in 25 Kg Kraft paper bags Fermenta Biotech Ltd.


Buildings and Facilities • Total Plot area of the Kullu facility • Total built up area (API facility) Fermenta Biotech Ltd. : ~ 14170 m2 (Approx.) : ~ 3900 m2 (Approx.)

Manufacturing Site Information • The Site has dedicated Manufacturing Blocks for – Biocatalysts – API’s / Intermediates (Area ~ 3900 m2) • The APIs/Intermediate Block contains 3 separate Productions Plants: – Plant 1 : Dedicated plant for Manufacturing of Cholecalciferol – Plant 2 : Multipurpose Plant for Manufacture of APIs / Intermediates – Plant 3 : Dedicated plant for Manufacture of Activated Dimethicone • Kosher , Halal certified and WHO GMP certified • Strict adherence to Safety, Health & Environment (SHE) policy Fermenta Biotech Ltd.

Manufacturing Shop-floor Cholecalciferol Fermenta Biotech Ltd.

Thank You Fermenta Biotech Ltd.

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