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Eve PJ4 Figure 1: evePJ4 behaves as a hypomorphic allele

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Information about Eve PJ4 Figure 1: evePJ4 behaves as a hypomorphic allele
Health & Medicine

Published on February 6, 2009

Author: jme17

Source: slideshare.net

Description

Figure of 4 representative genotypes at 3 developmental stages (Bownes Stages): WT (control), eve3 (null mutant), evePJ4, evePJ4wgNE2.
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Stage 9 Stage 10 Stage 11 WT eve3 evePJ4 wgNE2evePJ4 Figure 1: evePJ4 behaves as a hypomorphic allele. Comparison of wingless protein expression from immunofluorescent microscopy. Anti-wingless antibody was used to probe for wingless protein (wg) expression. eve3 is a known amorph resulting in a loss of wg expression. evePJ4 exhibits loss of wg patterning resembling the eve3 amorphic phenotype; however wg is still produced. wgNE2evePJ4 exhibits wg patterning that more resembles the wild-type phenotype. Embryos are orientated with anterior to left and dorsal up. (Ko, M., Lau, J., and Mendoza-Elias, J. Bio205L September 2006)

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