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emka TECHNOLOGIES - isolated organs - emkaBATH4 tissue bath system

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Information about emka TECHNOLOGIES - isolated organs - emkaBATH4 tissue bath system
Technology

Published on February 14, 2014

Author: emkaTECHNOLOGIES

Source: slideshare.net

Description

What is the emkaBATH4 system?

Integrated and compact solution for studying the contractile properties of isolated tissue:

aortic rings
trachea
papillary muscles
atrium
uterus
...

The intelligent setup that takes care of technical details so you can concentrate on your data!

http://isolated-organ.emka.fr/
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emkaBATH4 tissue bath system smart tools – swift services – sharp research www.emka.fr

1 - what is the emkaBATH4 system? APPLICATIONS SYSTEM OVERVIEW 2 - how does it work? AUTOMATION STAND-ALONE USE OR SOFTWARE CONTROL DATA ACQUISITION STIMULATION 3 - why use it?

what is the emkaBATH4 system? integrated and compact solution for studying the contractile properties of isolated tissue aortic rings trachea papillary muscles atrium uterus ...

what is the emkaBATH4 system? all-in-one mainframe • 4 baths with transducers & amplifiers • bath temperatures adjusted and controlled electronically • automated bath filling/emptying • automated tissue tensioning with motors smart tools – swift services – sharp research www.emka.fr

what is the emkaBATH4 system? integrated hardware • pump for pushing perfusate to baths • emptying pump for drawing perfusate from the baths smart tools – swift services – sharp research www.emka.fr

what is the emkaBATH4 system? integrated hardware • motors for tissue tensioning • heating elements • signal amplifiers smart tools – swift services – sharp research www.emka.fr

what is the emkaBATH4 system? the emkaBATH4 mainframe comes with: • a power supply unit • a perfusate reservoir • container for used perfusate smart tools – swift services – sharp research www.emka.fr

what is the emkaBATH4 system? large range of hooks designed to facilitate tissue manipulation range of bath sizes • 20ml • 10ml • 5ml smart tools – swift services – sharp research www.emka.fr

what is the emkaBATH4 system? custom-designed it50 isometric transducers • robustness • sensitivity smart tools – swift services – sharp research www.emka.fr

what is the emkaBATH4 system? custom-designed it50 isometric transducers • stainless steel body • 0-50 g (0 - 0.5 N) measuring range • displacement: 0.89 mm/50g • sensitivity@Vcc=5V: 0.1 mV/g smart tools – swift services – sharp research www.emka.fr

what is the emkaBATH4 system? microvessel study • easily adapted for the study of up to 4 microvessels • for vessels of diameter 100μm to 3 mm and up to 3.5mm long • each microvessel bath incorporates its own isometric transducer, measuring forces up to 30g smart tools – swift services – sharp research www.emka.fr

how does it work? mainframe control panel provides access to all operations • set temperature : perfusate is heated to the required temperature as it travels to the bath • calibration : 0-1g / 0-10g / 0-50g smart tools – swift services – sharp research www.emka.fr

how does it work? mainframe control panel provides access to all operations • set tension (automated but manual override always possible) • fill, empty bath • wash, renew bath smart tools – swift services – sharp research www.emka.fr

how does it work? data acquisition with iox or other data acquisition software • USB connection to PC running iox software • information displayed on the control panel is sent to iox (temperature, tissue tension) • protocols can also be exported from iox • BNC outputs provide calibrated analog signal to any acquisition system smart tools – swift services – sharp research www.emka.fr

iox acquisition software designed for maximum productivity • full data display as graphs, tables, trends • beat to beat calculation on fast beating tissues (papillary/atrial muscles) • detailed calculation on slow contracting tissue (uterus, ileum) • on-the-fly comment and mark addition • preprogrammed action triggered by function key or timers • automated control of stimulators, valves, motors smart tools – swift services – sharp research www.emka.fr

datanalyst software powerful post-processing • data extraction • group averaging • ED50 • ... smart tools – swift services – sharp research www.emka.fr

how does it work? electrodes and stimulation • electrodes and stimulators are available from emka TECHNOLOGIES • third-party stimulators can also be used (iox control is not possible) smart tools – swift services – sharp research www.emka.fr

why use it? simple to set up and run • completely automated • easy mounting and removal for cleaning • corrosion-resistant • external connections and peripheral devices reduced to a minimum smart tools – swift services – sharp research www.emka.fr

why use it? smart features open system: analog outputs electric heating system for baths • faster response when compared to air heated systems to maintain temperature control • more accessible baths when compared with air heated system smart tools – swift services – sharp research www.emka.fr

why use it? smart features modular solution design • customization (i.e. bath sizes, tissue-holder, additional measurements such as pH, etc.) • up to 16 simultaneous baths with software control smart tools – swift services – sharp research www.emka.fr

why use it? smart features seamless hardware/software integration • all bath operations are accessible from within the acquisition software • filling/emptying and/or tissue tension operations are all set in the acquisition protocol (no need of a separate tissue bath control application) • quality control: tissue tension, and temperature data recorded smart tools – swift services – sharp research www.emka.fr

why use it? smart features fast fill, and empty of baths pumps for liquid control overflow-based bath renewal tissue is never exposed to air: no risk of drying! easy calibration smart tools – swift services – sharp research www.emka.fr

www.facebook.com/emkatechnologies @emkaTECH

solutions for lifesciences research www.emka.fr

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