advertisement

Dose Ranges

50 %
50 %
advertisement
Information about Dose Ranges
Health & Medicine

Published on March 16, 2009

Author: fovak

Source: slideshare.net

advertisement

Ionizing Radiation Cancer Radiotherapy: Whole body, acute: G-I destruction; lung damage; cognitive dysfunction Dose Ranges Whole body, acute: total dose to tumor (death certain in 5 to 12 days)* cerebral/ vascular breakdown (death in 1-5 days)* ( Rem ) 0 2000 4000 6000 8000 10,000 rem Total Body Whole body, acute: circulating blood Whole body, acute: marked G-I Irradiation Life Span Study cell death; moderate G-I damage and bone marrow damage (TBI) Therapy (death probable in 2-3 weeks)* (A-bomb survivors) (death probable in 1-2 weeks)* *Note: Whole body acute prognoses assume no 0 200 400 600 800 1,000 rem Estimated dose for medical intervention.) Human LD50 range, acute exposure Human LD50 range, acute exposure 3-yr Mars mission with no medical intervention with medical intervention (50% death in 3-6 weeks)* Evidence for small increases in Cancer Epidemiology human cancer above 10 rem acute exposure, 20 rem chronic exposure Typical mission doses on 0 20 40 60 80 100 rem Medical Diagnostics, rem Int. Space Station (ISS) NRC guideline for lifesaving ~ 25 rem A- Chest x-ray (1 film) 0.01 “Radiological DOE Low Dose Program Emergency” guidelines B- Dental oral exam 0.16 for public relocation I H J C- Mammogram 0.25 “Full-body CT screening” D- Lumbosacral spine 0.32 (one scan) 0 1 2 3 4 5 6 7 8 9 10 rem NRC Dose Limit for Workers DOE administrative control E- PET 0.37 Typical annual doses for = 5 rem/yr = 50 mSv/yr = 2 rem/yr = 20 mSv/yr commercial airline F- Bone (Tc-99m) 0.44 Medical Diagnostics (A-J) flight crews C DE G- Cardiac (Tc-99m) 0.75 A B F G H- Cranial CT (MSAD) 5 0 200 400 600 800 1,000 mrem = 1 rem (multiple scan average dose) Cleanup criteria for Natural background, background, Temporary “Special Case” annual I- Barium contrast G-I 8.5 average ≅ 300 mrem/yr site decommissioning/ Public Limit (NRC, DOE) fluoroscopy (2 min scan) license termination (includes radon) (~ four orders of Regulations & Guidelines 25 mrem/yr magnitude ) J- Spiral CT 3 - 10 Round-trip NY to London LD50 = Lethal Dose to 50% 0 10 20 30 40 50 60 70 80 90 100 mrem (the acute whole body dose that results in lethality to 50% of the exposed individuals) ANSI standard N43.17 NRC Dose Limit for Public Typical maximum NCRP Personnel scanner, 100 mrem/yr = 1 mSv/yr Absorbed dose: 100 rad = 1 Gray doses from DOE “Negligible max = 25 mrem/yr (DOE, ICRP, NCRP) facility releases Dose” Dose equivalent: 100 rem = 1 Sievert 100 mrem = 1 mSv Note: This chart was constructed with the intention of providing a simple, user-friendly, “order-of-magnitude” reference for radiation quantities of interest ( Chart compiled by NF Metting, Office of Science to scientists, managers, and the general public. In that spirit, most quantities were expressed in the more commonly used radiation protection unit, the rem (or Sievert, 2nd page), and medical doses are not in “effective” dose. It is acknowledged that the decision to use one set of units does not address (1 rem = 1 rad for x- and gamma- rays) DOE/BER; 24Jan2005,“Orders of Magnitude”) everyone’s needs. Disclaimer: Neither the United States Government nor any agency thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information disclosed.

Ionizing Radiation Cancer Radiotherapy: Whole body, acute: G-I destruction; lung damage; cognitive dysfunction Dose Ranges Whole body, acute: total dose to tumor (death certain in 5 to 12 days)* cerebral/ vascular breakdown (death in 1-5 days)* ( Sievert ) 0 10 20 30 40 50 60 70 80 90 100 Sv Total Body Whole body, acute: circulating blood Whole body, acute: marked G-I Irradiation Life Span Study cell death; moderate G-I damage and bone marrow damage (TBI) Therapy (death probable in 2-3 weeks)* (A-bomb survivors) (death probable in 1-2 weeks)* *Note: Whole body acute prognoses assume no 0 1 2 3 4 5 6 7 8 9 10 Sv Estimated dose for medical intervention.) Human LD50 range, acute exposure Human LD50 range, acute exposure 3-yr Mars mission with no medical intervention with medical intervention (50% death in 3-6 weeks)* Evidence for small increases in Cancer Epidemiology human cancer above 0.1 Sv acute exposures, 0.2 Sv chronic exposure Typical mission doses on 0 0.2 0.4 0.6 0.8 1 Sv Medical Diagnostics, mSv Int. Space Station (ISS) NRC guideline for lifesaving ~ 0.25 Sv A- Chest x-ray (1 film) 0.1 “Radiological DOE Low Dose Program Emergency” guidelines B- Dental oral exam 1.6 for public relocation I H J C- Mammogram 2.5 “Full-body CT screening” (one scan) 0 10 20 30 40 50 60 70 80 90 100 mSv D- Lumbosacral spine 3.2 NRC Dose Limit for Workers DOE administrative control E- PET 3.7 Typical annual doses for = 50 mSv/yr = 5 rem/yr = 20 mSv/yr = 2 rem/yr commercial airline F- Bone (Tc-99m) 4.4 Medical Diagnostics (A-J) flight crews C DE G- Cardiac (Tc-99m) 7.5 B A F G H- Cranial CT (MSAD) 50 0 2 4 6 8 10 mSv (multiple scan average dose) Cleanup criteria for Temporary “Special Case” annual ( = 1 rem ) Natural background, background, site decommissioning/ I- Barium contrast G-I 85 average ≅ 3 mSv/yr Public Limit (NRC, DOE) license termination fluoroscopy (2 min scan) (~ four orders of (includes radon) Regulations & Guidelines 0.25 mSv/yr magnitude ) J- Spiral CT 30 - 100 Round-trip NY to London LD50 = Lethal Dose to 50% 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1 mSv (the acute whole body dose that results in lethality to 50% of the exposed individuals) ANSI standard N43.17 NRC Dose Limit for Public Typical maximum NCRP Personnel scanner, = 1 mSv/yr = 100 mrem/yr Absorbed dose: 1 Gray = 100 rad doses from DOE “Negligible max = 0.25 mSv/yr (DOE, ICRP, NCRP) facility releases Dose” Dose equivalent: 1 Sievert = 100 rem 1 mSv = 100 mrem Note: This chart was constructed with the intention of providing a simple, user-friendly, “order-of-magnitude” reference for radiation quantities of interest ( Chart compiled by NF Metting, Office of Science to scientists, managers, and the general public. In that spirit, most quantities were expressed in the more commonly used radiation protection unit, the rem (or Sievert, 2nd page), and medical doses are not in “effective” dose. It is acknowledged that the decision to use one set of units does not address (1 Sv = 1 Gy for x- and gamma- rays) DOE/BER; 24Jan2005,“Orders of Magnitude”) everyone’s needs. Disclaimer: Neither the United States Government nor any agency thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information disclosed.

Add a comment

Related presentations

Related pages

US Department of Energy, Dose Ranges Rem Chart.

Title: US Department of Energy, Dose Ranges Rem Chart. Author: Noelle F Metting, Office of Science Created Date: 7/12/2010 10:16:29 AM
Read more

DOE Ionizing Radiation Dose Ranges ( Rem ) Chart

DOE Ionizing Radiation Dose Ranges ( Rem ) Chart - Free download as PDF File (.pdf), Text File (.txt) or read online for free.
Read more

Calculating Safe Medication Dose Ranges ... - Examples

This learning activity is designed to give nursing students confidence and skill with calculating safe dose medication ranges used in the clinical setting.
Read more

Dose Ranges placemat Oct08 - Fallout Radiation.com

Dose Ranges ( Rem ) 0 ... (or Sievert, 2nd page), and medical doses are not in “effective” dose. It is acknowledged that the decision to use one
Read more

SRIM Tutorial 1 - Ion Ranges, Doses and Damage

Page 1 of 6 . Tutorial #1- Introduction to Ion Ranges, Doses and Damage This Tutorial will cover how to find the energy and dose of ions required to ...
Read more

Comparison of the efficacy and safety of rosuvastatin ...

Across dose ranges, rosuvastatin reduced total cholesterol significantly more (p <0.001) than all comparators and triglycerides significantly more ...
Read more

dose range definition | English dictionary for learners ...

dose range meaning, definition, English dictionary, synonym, ... Search dose range and thousands of other words in English Cobuild dictionary from Reverso.
Read more