Cubosomes - Technology Landscape Overview

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Information about Cubosomes - Technology Landscape Overview

Published on October 26, 2016

Author: ruchicakumar

Source: slideshare.net

1. CUBOSOMES TECHNOLOGYTHROUGH PATENT GLASS RUCHICA KUMAR

2. WHY USE PATENTS ASTECHNOLOGY INDICATOR  Patents provide clear idea of number of players in market for a particular technology and key interest areas of all players.  Patent data provides an accurate understanding of problems a particular invention is aiming to resolve.  Patent data helps to understand how technology has changed over the years. For example, patent data can provide evidence of what technical domains were being researched into a decade ago as compared to technical domains being researched today.  Such a comparison helps in mapping out progress of a technology, knowledge externalities and cross industry innovation prospects  All the above mentioned points barely scratch the surface of ocean that is patent data analysis  In this report we aim to present few exemplary conclusions that we could draw from a detailed analysis of cubosome technology. 02-11-2016 RUCHICA KUMAR, NOVOCUS LEGAL LLP 2

3. WHAT ARE CUBOSOMES  Cubosomes are discrete, sub-micron, nanostructured particles of the biscontinuous cubic liquid crystalline phase.  Cubosomes are liquid crystalline nano-structures formed from the cubic phase of lipids, such as monooleate, or any other amphiphilic macromolecules with the unique property to be dispersed into particles.  Cubosomes are formed at controlled temperatures into lipid bi-layer twisted into three dimension with minimal surface forming a tightly packed structure with bicontinuous domains of water and lipid.There are three different proposed phases that these cubic structures can be in: the P-surface, G-surface and D-surface for primitive, gyroid and diamond structures respectively.  Cubosomes consist of honeycombed (cavernous) structures separating two internal aqueous channels and a large interfacial area. 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 3

4. FORMATION OF CUBOSOMES  Cubosomes can be manufactured by two distinct methods 1. Top down technique - It is the most widely used in research area, where by bulk cubic phase is first produced and then dispersed by high energy processing in to cubosomes nanoparticles. Bulk cubic phase is resembling a clear rigid gel farmed by water swollen crossed linked polymer chains, where as cubic phases are like liquid crystalline structure.The cubic phases exhibits a yield stress that increases with increasing amount of bilayer forming surfactant and oils 2. Bottom up technique - In this cubosomes are allowed to form or crystallize from precursors.Almgren et., al. discuss the formation of cubosomes by dispersing inverse micellar phase droplets in water at 80ºc,and allow them to slowly cool, gradually droplets get crystallizes to cubosomes.This is more robust in large scale production of cubosomes. 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 4

5. LANDSCAPE OF CUBOSOME TECHNOLOGY  We have analysed patents related to cubosome technology from year 2006 to 2016.  This analysis has been undertaken for fulfilling following objectives:  To understand evolution of cubosome technology, and to map out its progress in terms of key players, geographical distribution.  To identify new research areas and new licensing opportunities in field of cubosome technology  To map out applications of cubosome technology, in order to understand new investment or commercialization opportunities  To study Technology competitiveness amongst various key players and various jurisdictions in order to determine technology influence and market power of various key players jurisdictions. 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 5

6. AIMS OFTHIS PRESENTATION  This presentations aims to present an overview of this study related to cubosome technology.  The presentation would include few charts from the original study and basic explanation of each chart.  Detailed explanation, inferences, conclusions and majority of analysis charts have not been included in this presentation for purpose of retaining simplicity in the presentation.  Interested candidates may contact the author for complete analysis and report. 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 6

7. EVOLUTION OF CUBOSOME TECHNOLOGY FROM 2006-2016 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 7 CN DE EP FR IN JP KR PCT RU US0 5 10 15 20 25 30 35 40 45 1999 2000 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 1 1 0 0 3 7 7 9 19 38 45 44 21 21 41 6 0 0 2 5 8 8 3 7 7 9 8 7 11 6 4 1 CubosomeTechnology Progression over the years and across the globe CN DE EP FR IN JP KR PCT RU US

8. KEY PLAYERS – CUBOSOME TECHNOLOGY 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 8 24 20 21 5 5 5 5 4 4 4 4 3 3 3 3 3 3 0 5 10 15 20 25 30 Guardian Industries Corp. Univ Dalian Tech Selecta Biosciences Knu-Industry Cooperation Foundation The Regents Of The University Of California Univ Jilin Utc Power Corporation Shin In Ja Technion Research And Development Foundation Ltd. Univ Nanjing Virun 3M Innovative Properties Company Beijing Institute Of Technology Guardian Industries Corp (Us) Korea Institute Of Science And Technology Nanjing University Seagate Technology Llc Key Players - CubosomeTechnology

9. TECHNICAL AREAS UNDER CUBOSOME TECHNOLOGY 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 9 0 10 20 30 40 50 47 40 27 23 22 21 21 19 19 17 15 15 14 13 11 TechnicalAreas under CubosomeTechnology Medical Preparations Use of Metallic Compounds for Cubosome formation Material Analysis Heat exchange materials Nanofabrication 0 2 4 6 8 10 12 14 16 18 0 0 17 0 0 2 1 3 0 0 0 4 0 1 0 1 2 0 0 0 0 0 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 TechnicalArea Distribution in terms of Key Players

10. CO-ASSIGNMENT – JOINTVENTURES 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 10 4 1 1 2 2 1 1 1 1 1 1 1 1 1 0 0.5 1 1.5 2 2.5 3 3.5 4 4.5 Shin In Ja Beijing Institute Of Technology Children&Apos;S Hospital Medical Center Immundiagnostik Ag Ocean&Apos;S King Lighting Science &Amp; Technology Co. Tsinghua University Anhui Zhongchuang Electronic Information Material Co Ltd Baxter International Inc. Bengbu Glass Ind Design Inst Catholic Kwandong University Industry Foundation Centre Nat Rech Scient Centre National De La Recherche Scientifique China Petroleum &Amp; Chemical Corporation Ehnsehrm (Ehnstitju Nas&Apos;Onal&Apos; De Lja Sante Eh… Number of Applications as a JointVenture and Players involved Details available in full report

11. TECHNOLOGY INFLUENCE OF KEY PLAYERS 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 11 14.83 0 11.2 3 3.6 1 0.5 3.75 22 5.75 0.67 0.67 0.5 2.75 1.25 0 1 1.67 2 1.5 1.67 0 1.67 2.33 0.5 0 0 0 0 2 0 5 10 15 20 25 Technology Influence

12. MARKET POWER OF KEY PLAYERS 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 12 21.67 1 37 2 1 1 7.4 2.8 10 5 9 9 10 1 1.5 18.67 8 1 8 2 1.33 50 1 1 10 6 1 6 5 4 0 10 20 30 40 50 60 Market Power of key players – CubosomeTechnology

13. COMPARISON OFTECHNOLOGY INFLUENCE AND MARKET POWER OF KEY PLAYERS 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 13 0 5 10 15 20 25 30 35 40 45 50 14.83 0 11.2 3 3.6 1 0.5 3.75 22 5.75 0.67 0.67 0.5 2.75 1.25 0 1 1.67 2 1.5 1.67 0 1.67 2.33 0.5 0 0 0 0 2 21.67 1 37 2 1 1 7.4 2.8 10 5 9 9 10 1 1.5 18.67 8 1 8 2 1.33 50 1 1 10 6 1 6 5 4 Comparison - Key Players Technology Influence Market Power

14. APPLICATIONS OF CUBOSOME TECHNOLOGY 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 14 2010 2011 2013 2009 2006 2005 2016 0 2 4 6 8 10 12 14 16 18 Applications of CubosomeTechnologyVsYear of Application of Patent 2010 2012 2011 2015 2013 2014 2009 2008 2006 2007 2005 2004 2016 24 18 16 15 13 12 12 11 11 10 10 0 5 10 15 20 25 30 Applictions of Cubosome technology

15. SUMMARY  The presentation gives us an overview of cubosome technology along with its key players, and major applications.  We find upon detailed analysis of Citations, family size, applications of technology, problems solved by technology that cubosome technology has lot more potential that what is being tapped currently.  There is lot of scope of developing cubosome technology in fields of Medicine, Microscopy amongst others. Details are discussed in complete report available with the author. 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 15

16. ABOUTTHE AUTHOR  Mrs. Ruchica Kumar - An Intellectual Property professional and a registered patent agent who been working in the highly specialized and focused field of Patent Management. As a registered patent agent she has drafted and prosecuted various patent applications. Her work is focused on technical and strategic facets of patent management involving patent analytics, acquisition and management. Her area of specialization is patinformatics wherein, she leverages technical aspects of patent drafting, patent valuation and patent citations to generate comprehensive patent intelligence data. Her sound technical skill set amalgamated with a strong patent knowledge base provides her good understanding of dynamics of cross industry innovation.  Her competencies include: • Innovation Forecasting – Analyzing knowledge spill-overs and externalities for forecasting new innovation areas for an organization using patents as indicators • Patent Drafting in fields of Medical surgical devices and implants, cardiac rhythm management devices, urology, gynecology. • Patent Invalidation and Patentability assessment • Technology infusion and diffusion studies using patents as indicators • Licensing and Technology Transfer in fields of general engineering • Indian Patent filing and prosecution • Technology Mapping • Pre-litigation due diligence 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 16

17. CONTACT US • We welcome any queries regarding any of the topics you found interesting. We would be happy to provide more details on any of the topics you desire. Also, any queries regarding any issues related to intellectual property are most welcome. • We can be reached at:  Phone: +91-971-154-16163  Email: rkumar@novocuslegal.com, akumar@novocuslegal.com  Web: http://novocuslegal.com/index.php 02-11-2016RUCHICA KUMAR, NOVOCUS LEGAL LLP 17 Disclaimer: This report was not prepared as an account of work sponsored by any agency. Neither the author nor any agency thereof, nor any of their employees, nor any of their contractors, subcontractors or their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or any third party's use or the results of such use of any information, apparatus, product, or process disclosed, or represents that its use would not infringe privately owned rights. Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise, does not necessarily constitute or imply its endorsement, recommendation, or favoring by the author or any agency thereof or its contractors or subcontractors. The views and opinions of author expressed herein do not necessarily state or reflect any factual or strategic inference. This report is for reference and illustration purpose only and should not be used for commercial purposes.

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