Community Acquired MRSA & Animal Bites

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Information about Community Acquired MRSA & Animal Bites

Published on May 25, 2008

Author: ah.alraiyes

Source: slideshare.net

Description

This case will help you managing the community acquired coetaneous MRSA wounds and antibiotics choice plus animal bites pathology and management

 Methicillin resistance in S. aureus is defined as an Oxacillin (MIC) > 4 microgram/mL. Isolates resistant to oxacillin or methicillin are also resistant to all beta - lactam agents including cephalosporins.

 The mecA gene responsible for methicillin resistance  Staphylococcal cassette chromosome (SCCmec).  There are five SCCmec types (I-V) that vary in genetic makeup and size.

Hospital Associated Community Associated MRSA MRSA HA - MRSA CA - MRSA type I, II, or III SCCmec type IV SCCmec does not carry the multiple antibiotic resistance Sensitive to Bactrim, Clindamycin & Multiple antibiotic resistance 50% fluoroquinolones. Panton-Valentine leukocidin •SCCmec type IV CA-MRSA •skin •soft tissue •necrotizing pneumonia Prolonged hospitalization •MRSA USA300

12-29%

 Prior skin infection  Previous antibiotic use  Illicit drug use  Tattoo recipients  Prison residence  Military personnel  A higher body mass index  Cosmetic body shaving  Physical contact with a person who has a draining lesion or is a carrier of MRSA  Sharing equipment that is not cleaned or laundered between users

 Antibiotic use within three months before admission.  Hospitalization during the past 12 months.  Diagnosis of skin or soft-tissue infection at admission  HIV infection

 Skin or soft tissue infections.  Necrotizing pneumonia.  Necrotizing fasciitis  Rapidly fatal septicemia  Endocarditis  Osteomyelitis

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