Coagulation disorder

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Information about Coagulation disorder
Education

Published on March 6, 2014

Author: nusratjitu1

Source: authorstream.com

COAGULATION DISORDER: COAGULATION DISORDER Blood coagulation- a process in which liquid blood is changed into a semisolid mass(a blood clot). : Blood coagulation- a process in which liquid blood is changed into a semisolid mass(a blood clot). Blood coagulation disorder : A disturbance in the normal clotting mechanism of the blood. Coagulation disorders can be lead to the increased risk of bleeding(hemorrhage) or abstructive clotting(thrombosis) Coagulopathies: : Coagulopathies : H ereditary deficiency or abnormality of a single coagulation factor. Hemofilia A (FVIII) Hemofilia B (FIX) Von Willebrand’s disease Rare coagulopathies (FI. II. V. VII. X. XI. XIII) Aquired generally several coagulation abpresent. - Deficiencies of the vitamin K normalities are dependent coagulation factors (FII, VII, IX, X) He patic disorders Accelerated destruction of blood coagulation (DIC) Inhibitors of coagulation Others (massive transfusion, extracorporal circulation ) :  Hemophilia A bleeding disorder in which clotting factor VIII (eight) /hemophilia A or IX (nine) hemophilia B in a person‘s blood plasma is missing or is at a low level . Hemophilia A and B are X-linked disorders whereas Hemophilia C is much more rare. Cause: Females carrier of hemophilia has the hemophilia gene on one of her chromosome and there is a 50% chance that she may pass the defective gene to her male offspring. Males that hemophilia do not pass the gene to thair sons;they do pass the gene to their daughter. Symptoms: Excessive or uncontrollable bleeding. Bleeding may occure even if there is no injury. :  People with hemophilia should : - Exercise and stay fit. - Wear protection that is appropriate for the sport or activity. - Get regular check-ups that include joint and muscle examination. - A person with hemophilia needs to control his weight so that he does not put extra stress on his joints, especially if he has arthritis. Hemophilia is a lifelong disease: The level of factor VIII or IX in his blood usually stays the same throughout his life Treatment: Blood transfusion. The only mode of treatment is to inject the missing clotting factor into a vein. Von willbrand disease- The most common hereditary disorder is caused by a deficiency or dysfunction in an important clotting factor called von willbrand factor(VWF) which mediates the binding of glycoprotein lb(GPlb) to collagen .: Von willbrand disease- The most common hereditary disorder is caused by a deficiency or dysfunction in an important clotting factor called von willbrand factor(VWF) which mediates the binding of glycoprotein lb( GPlb ) to collagen . Dental health is very important in haemophilia : Healthy teeth and gums reduce the need for haemophilia treatment. - Regular dental care reduces the need for injections and surgery. Antibiotics may be required to help reduce the initial inflammation. Symptom-Abnormal menstrual bleeding -Bleeding of the gums -Skin rash : Symptom -Abnormal menstrual bleeding -Bleeding of the gums -Skin rash Treatment : Von Willebrand disease is a lifelong condition with no cure.The most common treatment for Von Willbrand disease include- 1) Dismopression:This medication is administered by injection into a vein.It is a synthetic hormone. 2)Replacement therapies:Replacement of blood clotting factors containing VWF and factor VIII (eight) PowerPoint Presentation: THANK YOU

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