Causes of Mesothelioma

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Information about Causes of Mesothelioma
Health & Medicine

Published on March 10, 2014

Author: cvlysed

Source: slideshare.net

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learn more about the causes of mesothelioma: asbestos, simian virus 40 and others

auses of mesothelioma

Asbestos

Asbestos is the commercial name for a group of hydrated silicate fibrous materials. 1

Chrysotile Amosite Crocidolite Tremolite Serpentine Amphibole Anthophyllite Actinolite Asbestos is the commercial name for a group of hydrated silicate fibrous materials. 1 there are two types of asbestos 2

11 million exposed people between 1940-783

11 million exposed people between 1940-783 expected latency period after exposure 25-50 years

11 million exposed people between 1940-783 expected latency period after exposure 25-50 years sharp increase in mesothelioma cases in the US 1970s – 1990s leveled off in 1992

11 million exposed people between 1940-783 expected latency period after exposure 25-50 years sharp increase in mesothelioma cases in the US 1970s – 1990s asbestos regulations were passed1980s

11 million exposed people between 1940-783 expected latency period after exposure 25-50 years sharp increase in mesothelioma cases in the US 1970s – 1990s asbestos regulations were passed1980s trace amounts of asbestos may still be allowed legally

11 million exposed people between 1940-783 expected latency period after exposure 25-50 years sharp increase in mesothelioma cases in the US 1970s – 1990s asbestos regulations were passed1980s trace amounts of asbestos may still be allowed legally some developing countries still continue to use asbestos

11 million exposed people between 1940-783 expected latency period after exposure 25-50 years sharp increase in mesothelioma cases in the US 1970s – 1990s asbestos regulations were passed1980s trace amounts of asbestos may still be allowed legally some developing countries still continue to use asbestos All of this add up to the persistence of mesothelioma in the coming years

Country Production (metric tons) Russia 1,000,000 China 400,000 Brazil 270,000 Kazakhstan 214,000 Canada 100,000 Major Producers of Asbestos 5

Asbestos cement sheets Fire rated doors Asbestos cement pipes Low density insulating boards Brake pads replaced since 1995 Vinyl floor tiles Fireproofing Acoustic ceilings Gaskets Drilling fluid additives also in:  Mining  Ship building  Paper milling  Railroad repair  Ceramics Sources of Asbestos Sources of Asbestos

Carbon Nanotubes

Carbon nanotubes are allotropes of carbon with a wide array of applications in electronics, optics 4 Animal Models only similar dimensions and chemical property as asbestos

Carbon nanotubes are allotropes of carbon with a wide array of applications in electronics, optics 4 Animal Models only Single-walled Multi-walled Nanotorus Nanobud Grafinated Nitrogen doped Peapod Extreme Cup-stacked There are different types

What are the current applications of carbon nanotubes? Wind turbines Marine paints Ice hockey sticks Surf boards Baseball bats Maritime vessels Handlebars Seat posts Scaffolding for bone growth Golf clubs

Simian Virus 40

SV-40 is the 50s & 60s polio vaccine contaminant Mixed Reviews

SV-40 is the 50s & 60s polio vaccine contaminant Mixed Reviews 10-30 million people exposed to SV-40 contaminated polio vaccines 1955-63

BAP1 gene defects

Official Name: BRCA1 Associated Protein-1 Regulate key histones and transcription factors related to tumor development BAP1 gene is located on chromosome 3

Other Potential Causes

Radiation therapy Radiation to supradiaphragmatic fields Other Potential Causes

Radiation therapy Radiation to supradiaphragmatic fields Intrapleural thorium dioxide Other Potential Causes

Radiation therapy Radiation to supradiaphragmatic fields Intrapleural thorium dioxide Zeolites Other Potential Causes An example is erionite which is common in Turkey

References 1. Daniel H Sterman, MD, et al. Epidemiology of malignant mesothelioma. UpToDate version 19.3 2. Wikipedia, the free encyclopedia. Mesothelioma 3. National Institute of Health 4. Wikipedia, the free encyclopedia. Carbon nanotubes 5. U.S. Geological Survey, Mineral Commodity Summaries updated March, 2013

What Next? What are the symptoms of mesothelioma? How is mesothelioma diagnosed? What is the survival rate of mesothelioma? How is mesothelioma treated? Checkout mesosupport.blogspot.com to learn more. We will guide you through everything related to mesothelioma – from what’s to what of’s to laws to treatments

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