cancer 2

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Published on October 25, 2008

Author: directman

Source: authorstream.com

Proto-oncogen y genes Oncosupresores : Proto-oncogen y genes Oncosupresores Las mutaciones con ganancias de función convierten protooncogenes en oncogenes Los oncogenes se identificaron primero en retrovirus causantes de cáncer Retrovirus carcinogénicos de acción lenta pueden activar protooncogenes Slide 2: Muchos virus DNA también contienen oncogenes Las mutaciones con pérdida de función en genes oncosupresores de tumor son oncogénicas El primer gen oncosupresor se identificó en pacientes con Retinoblastoma hereditario Mutaciones Oncogénicas : Mutaciones Oncogénicas Que afecten la proliferación celular Que producen pérdida de control del ciclo celular Que afecten la estabilidad del genoma Slide 16: Investigación Prospectiva 1.-oncogenes 2.-Genes supresores de tumores 3.-factores de crecimiento y su receptor 4.-Sistema de reparación del DNA 5.-Regulación del ciclo celular

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