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Published on November 15, 2007

Author: Elodie

Source: authorstream.com

Refinement and Reduction The use of laparoscopy and ultrasonography in animal studies:  Refinement and Reduction The use of laparoscopy and ultrasonography in animal studies July 9, 2002 H. Borghys Laparoscopy / Ultrasonography:  Laparoscopy / Ultrasonography Techniques for visualization and sampling of fluids/ tissue in dogs Laparoscopy:  Laparoscopy - minimal invasive (keyhole technique) - general anesthesia (fentanyl/ACP + propofol) - samples/biopsies of different organs/tissues for histology, pharmacokinetics, pharmacology Laparoscopy:  Laparoscopy Liver Laparoscopy:  Laparoscopy Liver Intestines Laparoscopy:  Laparoscopy Liver Intestines Bile Ultrasonography:  Ultrasonography - non invasive - awake dogs - aid for biopsy Ultrasonography:  Ultrasonography Muscle Ultrasonography:  Ultrasonography Muscle Prostate Ultrasonography:  Ultrasonography Muscle Prostate Uterus Laparoscopy / Ultrasonography:  Laparoscopy / Ultrasonography Advantages - scientific - ethical: - minimal to non-invasive  less or no trauma - more efficient use of animals: own control, re-use 15% reduction of terminal dogs/year REFINEMENT REDUCTION Slide34:  QUESTIONS?

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