Antibiotics That Require Frequent Monitoring

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Information about Antibiotics That Require Frequent Monitoring

Published on May 9, 2008

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Antibiotics That Require Frequent Monitoring

Antibiotics that Require Frequent Monitoring (Aminoglycosides)

35 mcg/ml Peaks 5 mcg/ml Troughs Amikacin Drugs

 

10 mcg/ml Peaks 2 mcg/ml Troughs Gentamicin Drugs

 

35 mcg/ml Peaks 5 mcg/ml Troughs Kanamycin Drugs

 

16 mcg/ml Peaks 2 mcg/ml Troughs Neomycin Drugs

 

25 mcg/ml Peaks Varies Troughs Streptomycin Drugs

 

20 mcg/ml Peaks 2 mcg/ml Troughs Tobramycin Drugs

 

25 mcg/ml Peaks 5-10 mcg/ml Troughs Vancomycin Drugs

 

Aminoglycosides must be monitored carefully for side effects including ototoxicity (vestibular and cochlear), nephrotoxicity , neurotoxicity , and hypersensitivity reactions. Monitor patients for tinnitus, vertigo, hearing loss, rash, dizziness, or difficulty urinating. 

Aminoglycosides must be monitored carefully for side effects including ototoxicity (vestibular and cochlear), nephrotoxicity , neurotoxicity , and hypersensitivity reactions. Monitor patients for tinnitus, vertigo, hearing loss, rash, dizziness, or difficulty urinating. 

Renal lab tests that must be monitored include urinalysis, specific gravity, BUN, creatinine, and creatinine clearance. 

Renal lab tests that must be monitored include urinalysis, specific gravity, BUN, creatinine, and creatinine clearance. 

Liver lab tests that must be monitored include , AST (SGOT), ALT (SGPT), serum alkaline phosphatase, bilirubin, creatinien, and LDH concentrations.

Liver lab tests that must be monitored include , AST (SGOT), ALT (SGPT), serum alkaline phosphatase, bilirubin, creatinien, and LDH concentrations.

Trough# levels are referred to as the minimum drug concentration that proceeds the administration of a single dose of medication. Trough levels should be drawn just prior to the next dose

Trough# levels are referred to as the minimum drug concentration that proceeds the administration of a single dose of medication. Trough levels should be drawn just prior to the next dose

Peak* levels are referred to as the maximum drug concentration that follows the administration of a single dose of medication. Peak levels should be drawn 1 hour after IM injections and 30 minutes after a 30-minute IV infusion is completed. 

Peak* levels are referred to as the maximum drug concentration that follows the administration of a single dose of medication. Peak levels should be drawn 1 hour after IM injections and 30 minutes after a 30-minute IV infusion is completed. 

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