allergy facts

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Information about allergy facts

Published on January 14, 2008

Author: Bianca


ALLERGY FACTS:  ALLERGY FACTS PATHOPHYSIOLOGY:  PATHOPHYSIOLOGY Sensitization Early (acute) phase reaction Late phase reaction Chronic disease SENSITIZATION:  SENSITIZATION Previous exposure Produce IgE antibodies IgE antibodies attach to mast cells in tissues Eye, nose, lung, skin, GI tract EARLY PHASE REACTION:  EARLY PHASE REACTION Allergen attaches to IgE on mast cell Release of mediators Act on nerves, blood vessels Production of mediators Continue actions on blood vessels, nerves Recruit inflammatory cells Sneeze, itch, runny nose, stuffy nose LATE PHASE REACTION:  LATE PHASE REACTION 2-8 hours after initial reaction Same symptoms as early reaction Release of mediators from recruited cells Related to severity of early reaction CHRONIC DISEASE:  CHRONIC DISEASE Priming Need less allergen to trigger symptoms Hyperreactivity Symptoms from exposure to strong or irritating fumes or odors Inflammation Ongoing symptoms ALLERGIC TRIGGERS:  ALLERGIC TRIGGERS Dust mites Carpeting, upholstered furniture Animals Furry or feathered Pollens PE, recess ALLERGIC TRIGGERS II:  ALLERGIC TRIGGERS II Cockroaches Molds Water damage, leaking roofs, poorly maintained heating/cooling systems Outdoors and indoors Foods Uncommon for chronic symptoms NONALLERGIC TRIGGERS:  NONALLERGIC TRIGGERS Strong odors from cleaning agents, floor finishing agents, pesticides, fertilizer, etc Cigarette smoke Chalk dust Dry erase pens THERAPY:  THERAPY Avoidance of triggers Medications Allergy injections AVOIDANCE OF TRIGGERS:  AVOIDANCE OF TRIGGERS No carpeting or upholstered furniture No furry or feathered pets Perform maintenance chores requiring use of irritating chemicals/cleaners when children not present Maintain heating/cooling systems No smoking ALLERGY INJECTIONS:  ALLERGY INJECTIONS When medications and avoidance don’t work Usually prescribed by a specialist Effective for dust mites, cats, pollens When history confirms skin test results More properly called immunotherapy Additional Resources:  Additional Resources Allergy & Asthma Network/Mothers of Asthmatics, Inc. -- American Academy of Allergy, Asthma, and Immunology -- American Academy of Pediatrics -- American College of Allergy, Asthma, and Immunology -- Additional Resources:  Additional Resources Asthma & Allergy Foundation of America -- US Environmental Protection Agency --

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