1. Passive transport

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Information about 1. Passive transport

Published on February 26, 2014

Author: husanbano

Source: authorstream.com

TRANSPORT THROUGH CELL MEMBRANE: TRANSPORT THROUGH CELL MEMBRANE Husan Bano Associate Professor Department of Physiology Al- Tibri Medical College ISRA University Cell Membranes : Cell Membranes Key Concepts: It is biological membranes. It is selective membrane. Some substances crosses the membrane by diffusion Some substances require energy to cross the membrane Large molecules cross the membrane via vesicles. PowerPoint Presentation: Components of Plasma Membrane Lipids Proteins 1. Phospholipids 2. Cholesterol 3. Glycolipds 1. Peripheral Protein ( Associated) 2. Integral Protein (Membrane Spanning) 3. Glycoproteins ~50% ~50% Lipid Bilayer: Lipid Bilayer Hydrophilic heads Hydrophobic tails PowerPoint Presentation:  Embedded in the lipid bilayer Integral proteins span the membrane Peripheral proteins are on one side or the other of the membrane Protein of Cell Membrane Proteins—For Function: Proteins—For Function Carrier Receptors Enzymes Support Pump Carrier protein: Carrier protein Receptor protein: Receptor protein Enzymatic protein: Enzymatic protein eg . G-protein cascade Molecular Structure of Membrane :  Molecular Structure of Membrane Carbohydrates of membrane are located on the outer surface and can serve as recognition sites. Glycolipid — a carbohydrate bonded to a lipid Glycoprotein — a carbohydrate bonded to a protein Carbohydrate of Cell Membrane STRUCTURE OF CELL MEMBRANE: STRUCTURE OF CELL MEMBRANE Permeability of the Cell Membrane: Permeability of the Cell Membrane Permeability of the Cell Membrane: Permeability of the Cell Membrane PowerPoint Presentation: Transport Through C ell M embrane Transport through cell membrane: Transport through cell membrane Passive Transport Active Transport Endocytosis Exocytosis 1: PASSIVE TRANSPORT: Simple diffusion Facilitative diffusion Osmosis 1: PASSIVE TRANSPORT Types of Passive Transport 1: Simple Diffusion: 1: Simple Diffusion Definition: It is a process in which molecules (both solute and solvent) moves from higher to lower concentration Process of diffusion: Process of diffusion Gas exchange in lungs by diffusion: Gas exchange in lungs by diffusion PowerPoint Presentation: SIMPLE DIFFUSION THROUGH LIPID BILAYER SIMPLE DIFFUSION THROUGH LIPID BILAYER: SIMPLE DIFFUSION THROUGH LIPID BILAYER Following substances passes through lipid bilayer : CO 2 O 2 N 2 ALCOHOL H 2 O………………? (molecular size 0.3nm) Simple diffusion through lipid bilayer: Simple diffusion through lipid bilayer PowerPoint Presentation: SIMPLE DIFFUSION THROUGH Protein Channels SIMPLE DIFFUSION THROUGH PROTEIN CHANNAL: SIMPLE DIFFUSION THROUGH PROTEIN CHANNAL All the water soluble substances except charged particles passes through protein channels , not through lipid bilayer . Reason of impermeability is: They are hydrated ions. Outer pole of lipid bilayer have negative charge……… Hydrated Chloride (molecular size 3.6nm) SIMPLE DIFFUSION THROUGH PROTEIN CHANNAL: SIMPLE DIFFUSION THROUGH PROTEIN CHANNAL Simple Diffusion: Simple Diffusion 2: Facilitated Diffusion Facilitated Diffusion: Facilitated Diffusion Definition: It is the process in which molecules move from higher to lower concentration with the help of carrier protein . Facilitated Diffusion: Facilitated Diffusion Passive transport protein Lower concentration Higher concentration of REQUIRE: CARRIER No energy FASILITATED DIFFUSION: FASILITATED DIFFUSION Following substances passes through carrier proteins : Glucose Amino acids Other simple carbohydrates such as : Glactose Mannose Arabinose Xylose . All require “carrier protein” for their transpo rt, so called “carrier mediated diffusion” FASILITATED DIFFUSION: FASILITATED DIFFUSION Facilitative diffusion always has “ Vmax ” Simple Diffusion: Simple Diffusion 3: Osmosis 3: Osmosis :  3: Osmosis Movement of molecules by the process of osmosis create a pressure called osmotic pressure Definition: It is the process in which only solvent molecules move from higher to lower concentration through semi permeable membrane . What Is Osmotic Pressure?: What Is Osmotic Pressure? It is the pressure which prevent the process of osmosis. Osmotic pressure is measured in “ osmole or m.osmole . Best example of osmosis: Best example of osmosis Effect of isotonic , hypotonic and hypertonic solution on red blood cells: Solution Differences & Cells: Solution Differences & Cells solvent + solute = solution Isotonic Solutes equal inside & out of cell Hypotonic Solutes lesser outside cell than inside Water will flow into cell……………………..Cell Swell Hypertonic Solutes greater outside cell Water will flow out of cell………………….Cell shrink Impotent Points: Impotent Points The factors which determine the osmotic pressure is the conc. of solution in terms of number of particles, not the mass of solutes. Osmotic pressure is defined as the hydrostatic pressure required to stop the osmosis, and thus, osmotic and hydrostatic pressures are, for all intents and purposes, equivalent. PowerPoint Presentation: THANK YOU

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